Human activity is regulated by the sympathetic and parasympathetic nervous systems. These are antagonist systems: if the parasympathetic system provides peace (relaxes blood vessels, muscles and sphincters, reduces heart rate, etc.), then the sympathetic system is responsible for activating certain vital processes.
With prolonged excessive load, overexcitation becomes to a certain extent a “habitual” state, and psycho-emotional tension increases. It becomes increasingly difficult for a person to concentrate on a specific task. Sleep disorders appear (insomnia at night and drowsiness during the day) and exhaustion of the body increases (including physical exhaustion).
It is very difficult to cope with a problem of this kind on your own. An excellent tool for regulating the body's activity is the drug Glycine Evalar Forte. It belongs to the clinical and pharmacological group of drugs that improve brain activity.
Glycine formula
The chemical formula of glycine is: NH2 – CH2 – COOH.
This organic compound is classified as an aliphatic amino acid. The substance got its name due to its characteristic sweetish taste. In pharmaceuticals, this amino acid is used as a nootropic agent, that is, a compound that stimulates metabolic processes in the brain and improves the functioning of the nervous system as a whole. The substance is either synthesized or obtained through the hydrolysis of proteins.
Mechanism of action and pharmacodynamics
The drug provides regulation of metabolism in the central nervous system, which significantly increases mental performance. The amino acid glycine is characterized by antitoxic, GABAergic and α1-adrenergic blocking effects. It also has antioxidant properties, i.e. it minimizes the damaging effects of free radicals at the cellular and tissue levels.
The drug is able to normalize the process of falling asleep, reduce aggressiveness, and increase the ability of the central nervous system to adapt literally within a few days. When taken, the severity of vegetative-vascular disorders decreases and the process of restoring normal functioning of the central nervous system after ischemic strokes is accelerated.
B1 ensures the improvement of the nervous system. It helps improve cognitive abilities by stimulating metabolic processes in nerve cells.
B6 normalizes the activity of the central nervous system and improves the absorption of vitamin B12.
B12 ensures the regeneration of nerve tissue and is involved in the biosynthesis of the neurotransmitter acetylcholine.
When the tablet is dissolved, the components are absorbed very quickly and almost completely. During the process of biotransformation, they decompose into water and CO2 (carbon dioxide) within a short period of time. There is no cumulation (accumulation) observed.
Regular consumption of foods rich in this amino acid:
- increases mental performance,
- minimizes nervous tension,
- helps combat increased excitability and insomnia,
- reduces the toxic effects of ethanol,
- reduces the negative consequences of antibiotic therapy.
Glycine, which is directly involved in DNA synthesis:
- included in the course of treatment of traumatic brain injury or stroke within the first days,
- balances the processes of excitation and inhibition,
- eliminates irritability, anxiety and depression.
According to scientific publications, it is also capable of “slowing down” motor neurons of the spinal cord, which reduces the tone of skeletal muscles, for example, in epilepsy.
A unique amino acid improves the absorption of vital elements such as calcium and iron. The need for it increases sharply under conditions of emotional stress and during the period of rehabilitation after strokes and heart attacks.
Composition of the drug Glycine Forte Evalar
Composition of the drug Glycine Forte Evalar
The main component of the drug is Glycini, the chemical name of which is Aminoacetic acid. Glycine is involved in the regulatory processes of the spinal cord and brain, normalizes metabolic processes, and has anti-stress, nootropic, sedative and anti-epileptic effects.
Preparations with glycine are prescribed for diseases and undesirable manifestations such as:
- dementia is an acquired mental disorder that manifests itself as a decrease in intelligence;
- vascular dementia is a disease that develops as a result of cerebrovascular accident caused by brain damage;
- abstinence or withdrawal syndrome - occurs when you completely stop or reduce the dose of drugs or alcohol;
- dysthymia is a chronic condition characterized by depressed mood, but not reaching depression;
- anxiety and depressive disorder;
- unspecified mental retardation;
- behavioral disorders;
- disturbances in falling asleep and maintaining sleep;
- irritability and anger;
- state of emotional shock;
- lethargy and slow reaction;
- ailments and fatigue;
- consequences of intracranial injury.
Composition of the drug Glycine Forte Evalar
Glycine quickly penetrates the blood, breaking down and breaking down into carbon dioxide and water. It does not accumulate in the body and does not disrupt metabolic processes. Being an antioxidant, glycine neutralizes toxic substances in the body.
In addition to glycine, Glycine forte Evalar contains the following B vitamins:
— B6 (pyridoxine) – improves the absorption of unsaturated fatty acids. In tandem with calcium, it promotes normal muscle and heart function and their relaxation. A lack of vitamin B6 can lead to middle ear disease;
— B1 (thiamine) – participates in the energy supply of the brain, muscles, peripheral nervous system, reduces physical and mental fatigue, plays an important role in the prevention and treatment of encephalopathy and polyneuropathies, complicated by diabetes mellitus and alcoholism;
— B12 (cyanocobalamin) is the only substance containing the microelement cobalt, which is essential for health. Actively participates in the metabolism of proteins, carbohydrates and fats. The vitamin helps folic acid produce choline, which is responsible for keeping your nerves healthy and able to withstand everyday stress. B12 is responsible for the body’s iron reserves, and interacting with vitamin A, helps in the synthesis of body tissues.
Glycine forte Evalar
Thanks to this unique composition, Glycine forte Evalar quite gently and naturally at the most vulnerable - molecular level - reduces psycho-emotional stress, improving mood, relieving stress, normalizing the process of going to bed. Despite the fact that glycine does not dull memory, but, on the contrary, improves it and sharpens attention.
Just a couple of Glycine Forte tablets per day will help:
- cope with insomnia;
- improve emotional mood;
- actively resist stressful situations;
- increase mental performance;
Indications
Indications for taking Glycine Evalar Forte are:
- insomnia;
- increased excitability;
- prolonged psycho-emotional stress;
- forgetfulness;
- neuroses;
- neurotic conditions;
- cognitive impairment;
- suffered traumatic brain injuries;
- consequences of neuroinfections;
- deviant behavior (children and adolescents);
- perinatal encephalopathies;
- vegetative-vascular dystonia;
- rehabilitation after ischemic strokes.
The drug is prescribed to newborn children if intrauterine hypoxia has occurred.
Children from 1 to 2 years old need the amino acid with increased intracranial pressure.
For preschoolers and children of primary school age, glycine will speed up the learning process.
Indications for use
The medicine Glycine with B vitamins is indicated for nervous disorders without obvious damage to the structure and integrity of the brain, but with changes in its functions. This is manifested by insomnia, agitation and an unstable emotional state. Pathologies of the nervous system with a violation of the integrity and structure of the brain are also indications for treatment with Glycine. Such conditions can occur after injuries or previous infectious and inflammatory diseases, such as meningitis, encephalitis, and abscess. There are several other indications for the use of Glycine Forte:
- encephalopathy of perinatal, hepatic, alcoholic and other origins;
- dissomnia;
- bleeding in the brain;
- ischemic stroke;
- traumatic brain injury (TBI);
- increased anxiety, irritability;
- depression;
- epilepsy;
- rehabilitation after a heart attack;
- deviant behavior of adolescent children;
- chronic alcoholism;
- acute period of abstinence syndrome;
- reduced mental performance;
- stressful life situations.
Glycine Evalar Forte: instructions for use
Recommended daily doses are up to 1000 mg. For 7-30 days it is recommended to take 1 tablet 2-3 times a day.
The tablets are placed under the tongue or behind the cheek and held until completely absorbed. The sublingual (or transbuccal) form promotes maximum absorption and rapid achievement of a therapeutic effect.
For insomnia, it is recommended to take 1 tablet once a day 10-20 minutes before bedtime (for 7-14 days).
In case of ischemic stroke, in the first hours the victim is given 3 tablets at a time, and then for 5 days - 1 tablet. 3 times a day.
In drug treatment practice, to combat encephalopathies, patients are prescribed 1 tablet. 2-3 times a day. The duration of the course of treatment is 20-30 days. According to indications, courses can be repeated up to 6 times a year.
Analogs
- Glycine ozone.
- Glycine forte.
- Glycine-Bio.
- Glycine-Canon.
- Amylonosar.
- Glycine forte Evalar.
- Vinpotropil.
- Demanol.
- Diwaza.
- Cortexin.
When choosing analogues, it is important to understand that the instructions for use, price and reviews do not apply to drugs with similar effects. It is important to consult a doctor and not change the drug yourself.
Glycine or Glycine forte, which is better?
When wondering which Glycine is better, you need to pay attention to how Glycine and Glycine forte differ. The drugs have their differences.
The usual remedy is a drug consisting of one AMK. And Glycine forte is a biological supplement containing not only aminoacetic acid, but also B vitamins. The dietary supplement has a triple therapeutic effect; it saturates the body with natural neurotropic substances.
Also, when thinking about which Glycine to choose, you need to know that the medicine produced by Evalar contains 3-6 times more amino acid than the usual one. In addition, Glycine forte tablets contain a daily dose of useful substances necessary for the proper functioning of the nervous system.
But when thinking about which Glycine is best to consume or take, it is worth knowing that a regular amino acid in tablets costs about 75 rubles. And Evalar's dietary supplement costs several times more.
Which is better: Glycine or Tenoten?
These drugs have a similar effect on the body, but Tenoten does not have a sedative effect. This drug is a homeopathic remedy and is prescribed for children. The final decision on whether to take a particular drug should be made only by a doctor.
Glycine Bio and Glycine: differences
Glycine Bio provides a dual effect on the child’s body, reducing the degree of motor hyperactivity and at the same time improving learning ability and attention.
Glycine during pregnancy
If possible, it is advisable to abstain altogether from taking pharmacological agents during pregnancy. But in case of disorders of the nervous system against the background of hormonal changes in the body, the doctor may well recommend Glycine Evalar Forte to the expectant mother. In case of unstable mental state and increased fatigue, women are prescribed 1 tablet 2 times a day for 14 days. The dosage may be changed at the discretion of the attending physician (up to 3 times a day). You should not start taking the drug on your own initiative.
The duration of administration depends on the reason why you have to take the medicine and on the general condition of the patient. In many cases, Glycine Evalar Forte is the “drug of choice” for eliminating unwanted symptoms of nervous system disorders.
There is no reliable information about the complete safety of the product yet, but this is due to the fact that clinical trials have simply not been conducted. According to publications in medical journals, the active substances, even theoretically, cannot harm the unborn child.
You should be wary if allergic reactions occur - they are extremely undesirable during pregnancy. It is also recommended to refrain from taking this drug for patients with hypotension, as well as if there have been isolated cases of a significant decrease in blood pressure in the anamnesis.
