Comparison of Cavinton and Cavinton Forte
Cavinton forte or Cavinton are drugs used to eliminate cerebrovascular accidents.
Medicines have an antiaggregation effect on the body, promote vasodilation, improve and normalize blood flow in the brain.
Cavinton forte or Cavinton are drugs used to eliminate cerebrovascular accidents.
Interactions with other drugs
It is worth remembering that nootropics, while improving cerebral blood flow, also thin the blood and prevent platelet aggregation, so you should carefully prescribe them with anticoagulants. In cases of severe arrhythmia and hypertension, medications can be taken only after comparing the risks and benefits, because nootropics can prolong the QT interval.
It is also important to consider that drugs with metabolic effects on the brain can increase glucose levels in peripheral blood, which requires increased control for people with diabetes.
When collecting anamnesis, it is important to take into account the nephrotoxic effect of drugs that are used simultaneously with Piracetam. Therefore, when choosing a dosage, such patients should focus primarily on createnine clearance.
Characteristics of Cavinton
The drug is available in the form of tablets and concentrate for the preparation of infusion solution.
Cavinton contains the active component vinpocetine. In addition to the active substance, the tablets contain additional components that play a supporting role:
- talc;
- silicon dioxide;
- magnesium stearate;
- lactose monohydrate;
- corn starch.
In the composition of the concentrate for the preparation of infusion solution, the auxiliary compounds are:
- tartaric acid;
- sodium disulfite;
- water for injection;
- benzyl alcohol;
- ascorbic acid;
- sorbitol.
The tablet form is packaged in blisters; the tablets are white in color. The concentrate for the preparation of infusion solution is a clear liquid.
The main active ingredient belongs to the group of cerebrovasodilating agents. The use of the drug improves metabolism in tissue cells and blood supply to the brain. Cavinton is able to influence the rheological properties of blood. Under the influence of vinpocetine, the activity of transmembrane calcium and sodium channels, AMPA and NMDA receptors is inhibited.
Cavinton is able to influence the rheological properties of blood.
Under the influence of vinpocetine, the absorption and metabolism of oxygen and glucose by brain tissue cells improves, and the processes of serotonin and norepinephrine synthesis are activated. The drug is able to have antioxidant and stimulating effects on the noradrenergic system of the body.
Indications for use of the drug are extensive:
- in neurology - ischemia, vascular dementia, stroke, cerebral vascular atherosclerosis, vertebrobasilar insufficiency, post-stroke condition, hypertensive, post-traumatic encephalopathy and other types of cerebral circulatory failure, memory impairment, headaches and motor activity disorders;
- in ophthalmology - spasm of retinal blood vessels, atherosclerosis, degenerative diseases, development of secondary glaucoma, thrombosis, embolism;
- in otorhinolaryngology - age-related hearing loss, hearing impairment of toxic and vascular origin, cochleovestibular neuritis, Meniere's disease, dizziness, the appearance of tinnitus, vasovegetative manifestations in the menopause.
When prescribing the drug, one should take into account the patient’s possible contraindications to its use:
- severe forms of arrhythmia;
- severe ischemic heart disease;
- periods of lactation and gestation.
During the course of therapy, the patient may experience the following side effects:
- strengthening of existing arrhythmia;
- tachycardia;
- drop in blood pressure;
- dyspeptic disorders;
- dry mouth;
- heartburn;
- weakness;
- sleep disturbance;
- dizziness;
- migraine;
- allergy.
There is insufficient data on overdose; if such a situation occurs, it is recommended to perform gastric lavage and use activated charcoal. If necessary, symptomatic therapy is used.
To purchase a medicine at a pharmacy, you will need to present a prescription from your attending physician. The cost of the medicine depends on the form of the drug and ranges from 220 to 260 rubles. The shelf life of the medicine is 5 years.
Action of Cavinton forte
The pharmacological agent is available only in tablet form. The active component of the drug is vinpocetine.
Additional substances of the drug:
- talc;
- magnesium stearate;
- colloidal silicon dioxide;
- lactose monohydrate;
- corn starch.
The product is sold in packages of 30 and 90 tablets.
The drug improves blood circulation in brain tissue and has vasodilating, neuroprotective, antihypoxic and antiaggregation effects on the body.
Indications for use of the medicine are:
- states of cerebral circulatory insufficiency in order to reduce the symptoms of mental and neurological disorders;
- rehabilitation period after ischemic stroke;
- stage of recovery after hemorrhagic stroke;
- post-stroke complications;
- atherosclerosis of cerebral vessels;
- vascular dementia;
- transient ischemic attack;
- vertebrobasilar insufficiency;
- hypertensive or post-traumatic encephalopathy;
- therapy for idiopathic tinnitus;
- Meniere's disease and conditions associated with decreased perceptual hearing;
- chronic vascular pathologies of the organs of vision, including lesions of the retina and their choroid.
Indications for the use of the drug are conditions of cerebral circulatory failure.
Contraindications to the prescription of the drug are:
- IHD in severe form;
- periods of pregnancy and lactation;
- hemorrhagic stroke in the acute phase;
- hypersensitivity;
- age under 18 years;
- arrhythmias in severe form.
During therapeutic measures, the patient may experience undesirable reactions, manifested by:
- feeling of hot flashes;
- changes on the ECG;
- blood pressure lability;
- extrasystole;
- tachycardia;
- insomnia;
- hyperhidrosis;
- drowsiness;
- headaches;
- general weakness;
- dizziness;
- dry mouth;
- belching and heartburn;
- feeling of nausea.
Information on drug overdose is insufficient, but if it occurs, it is necessary to induce vomiting to cleanse the stomach, followed by the use of enterosorbents.
The drug is dispensed at the pharmacy only with a prescription. The shelf life of the medicine is 5 years. The cost of the drug can range from 250 to 300 rubles.
What are the differences and similarities between Cavinton and Cavinton forte?
Cavinton has more release forms compared to Cavinton Forte. Both drugs contain the same active ingredient.
Both drugs have similar indications for use, contraindications and side effects. Medicines must be taken after meals with plenty of water.
The selection of drug dosage depends on the type of pathology and individual characteristics of the body.
Cavinton forte contains 2 times more active component than Cavinton. This indicator affects the frequency of dosing of the drug.
Due to the higher content of the active component, the dosage regimen for the drug has been changed. It is recommended to take Cavinton forte 1-2 times a day, and Cavinton 3-4 times a day.
Instructions for use
Before starting treatment, you should consult with your doctor about how best to take Cavinton and Piracetam together. Despite the fact that the drugs interact well with each other, it is necessary to adhere to the rules of use for each of them.
Cavinton is administered only by slow intravenous infusion, which does not exceed 80 drops per minute. Intramuscular administration or administration without prior dilution is strictly prohibited.
The duration of therapy is individual and can last from 10 days to two weeks, after which the patient is transferred to oral nootropics or continues treatment with the tablet form of Cavinton. The initial dose averages 20 mg, and is subsequently increased at the rate of 1 mg per kg of patient body weight per day.
Piracetam is used only orally, which makes it possible to use it together with the infusion form of Cavinton, and the drugs act without reducing the bioavailability of each other. The duration of treatment and dose are selected individually for each patient depending on the severity of the condition, the severity of cognitive impairment, and the functional state of the kidneys.
Piracetam dosage
For elderly patients and people suffering from renal failure, dosage selection is carried out taking into account the indications of createnine clearance. For cognitive dysfunction, the initial dose is 4.8 g, which is divided into 2-3 doses. With the emergence of positive dynamics over time, the dosage is reduced until the average effective dose is established.
Doctors' opinion
Shkolnikov A.I., neurologist, Ryazan
Cavinton Forte was prescribed in such cases - headaches of vascular origin in cerebral atherosclerosis, as well as tinnitus. The drug can cause sudden changes in blood pressure. It makes sense to expect an effect only from 10 mg of the drug, but not at a dosage of 5 mg.
Mikhaleev M. A., psychotherapist, Samara
I use Cavinton Forte in small doses up to 5 mg per day when stopping antidepressant therapy. It is well recommended as part of complex treatment for asthenic and psycho-vegetative disorders, as well as night urination in children.
A good product that gives the expected results.
Kudryashov V.S., neurologist, Novosibirsk
Cavinton is an old, proven drug. Improves cerebral circulation, blood rheology, nutrition of brain structures. In practice, I use the tablet form of the drug. The minimum course is 1 month.
Effective for chronic cerebral vascular insufficiency and vegetative-vascular dysfunction. Use with caution when prescribing to patients with cardiac arrhythmias.
Lee D. G., neurologist, Yekaterinburg
Cavinton improves cerebral circulation and metabolic processes in brain tissue. It has proven itself in the treatment of the consequences of stroke, chronic cerebrovascular accident, encephalopathy of various origins, and vertebrobasilar insufficiency.
The disadvantage is a change in heart rhythm, which can provoke the appearance of tachycardia, extrasystole, and a decrease in blood pressure. As a result, it is necessary to take into account these criteria when prescribing it, especially in elderly patients.
The injection form contains sorbitol, which must be taken into account when prescribing to patients with diabetes.
Chepurnoy M. G., pediatric surgeon, Astrakhan
Cavinton improves blood circulation in the brain, prevents the formation of blood clots and thins the blood. I prescribe this drug to improve cerebral circulation in patients with ischemia, strokes, encephalopathies, and vertebrobasilar insufficiency. The product works well in eliminating the vegetative manifestations of menopause in women.
Drug compatibility
An important feature of nootropics is the possibility of their combination in therapy. Therefore, the patient can take Cavinton and Piracetam together. Both drugs will not only potentiate each other’s actions, but also have a full-fledged complex effect on brain cells.
If Piracetam is more likely to have an effect on cognitive processes, then Cavinton acts more like a neuroprotector. Both drugs successfully improve blood circulation in the blood vessels of the brain and help accelerate the delivery of the main energy substrates for nervous tissue - glucose and oxygen.
The effect on the exchange of neurotransmitters is safe due to the fact that Piracetam affects mainly the dopamine system, while Cavinton improves the exchange of norepinephrine and serotonin. When used in combination, it is possible to achieve an improvement in mood and level of wakefulness. The normothymic effect is complemented by a return of appetite, a decrease in anxiety and a decrease in the level of depression.
With the simultaneous use of two drugs, a pronounced antihypoxic effect is achieved. By restoring oxygen delivery, it is possible to restore the acid-base balance, which, with its antioxidant effect, reduces the cytotoxic damage to brain tissue.
