What happens if you drink Atarax with alcohol?

The rhythm of modern life is extremely high. People suffer from stress and are in constant tension. Sometimes this condition can last for a long period of time and lead to illness. According to statistics, at least 20% of Europeans suffer from various neuroses.

Anxiolytic drugs (otherwise called tranquilizers), which include the drug Atarax, help cope with the consequences of psychological and physical stress. Is it possible to take Atarax and alcohol at the same time? What could be the consequences?

Compatibility of Afobazole and alcohol

One of the most famous and effective is the sedative Afobazol. Taking alcohol and tranquilizers together is negative. Afobazole is an exception to the rule.

In order to avoid undesirable consequences and not interfere with the effect of the drug, you need to find out how to correctly and how long after you can take your favorite alcoholic drink after taking the medicine.

Afobazole is prescribed to patients with a depressed emotional state, anxiety, neurosis, and panic attacks. When treating a person with this drug, drinking alcohol is permitted by the instructions. The product does not lead the body to toxic poisoning upon contact with alcohol.

Disorders of the nervous system are manifested by neurotic conditions. In this state, a person ceases to control himself, and alcohol increasingly becomes his companion. Taking ethanol at some point dulls the severity of nervous reactions, but does not become a solution to the current situation.

Initially, drinking alcohol can provoke a beneficial effect. But such euphoria quickly passes, leaving an increased state of stress. Manifestations of aggression and anger are actively increasing.

Contact with alcohol is prohibited under the following conditions:

Bronchial asthma, allergies;
Cancerous tumors;
Heart diseases;
Stomach diseases;
Vegetative-vascular dystonia.

In the presence of diseases, taking ethanol can aggravate the problem and lead to serious consequences.

Alcohol, unlike medicine, has a lot of contraindications and side effects, take care of your health.

The drug ignores the treatment of alcoholism. To avoid manifestations of psychosis during a hangover, it is possible to use it, but the effect will occur in 3-4 days.

It is not possible to relieve a hangover syndrome with medicine; it will not be easy to stop the unpleasant symptoms, but as a tranquilizer it is considered effective and safe.

Consequences of drinking alcohol

Atarax is incompatible with alcoholic beverages! The drug and alcohol have a sedative effect on the central nervous system. Taking them together can provoke an overdose of the drug, which has negative manifestations. The person may even fall into a coma. In addition, the interaction of Atarax and ethanol has not been fully studied. Reactions can be the most unpredictable. There have been cases of patients admitted to medical institutions in whom taking Atarax with alcohol provoked:

convulsions;
hypertensive crisis (with blood pressure readings over 240/120, which is twice the norm and is a critical condition when a stroke is possible);
on the contrary, a sharp drop in blood pressure, even to coma;
difficulty breathing, inability to inhale;
uncontrolled and inappropriate aggression;
severe dizziness, inability to move in space because of this;
uncontrollable vomiting.

Doctors are unanimous in their opinion - Atarax and alcohol are prohibited from being taken together! In addition to the above, remember that any drug acts on the liver, since this organ is involved in removing drug breakdown products. Alcohol is undoubtedly even more harmful. It can lead to the rapid development of diseases such as cirrhosis. Combining Atarax with alcohol seriously undermines the functioning of the liver and other digestive organs, leading to intoxication, that is, poisoning.

a brief description of

The drug Afobazol is from the group of tranquilizers, has an activating effect, relieves anxiety. It has an unusually mild effect and is unlikely to cause addiction.

Indications for use:

Neurosis.
Panic states.
Insomnia.
Relief of alcohol syndrome.
Emotional adaptation when quitting smoking.
Premenstrual syndrome in women.

The drug is considered an assistant for blocking depression, anxiety, depression in people suffering from cardiovascular diseases. The tablets can be taken immediately in full dosage; the body does not need to get used to it.

Sedative therapy is contraindicated for expectant mothers, women breastfeeding, and children under adulthood. In other cases, a sedative can be taken without a doctor's prescription.

Consequences of taking the drug with strong drinks

The consequences of drinking alcoholic beverages will be unfavorable. Ethanol provokes neurotic conditions, which worsens the overall picture of the patient’s treatment.

If a tranquilizer was prescribed to treat mental illness, then drinking alcohol will only worsen the side effects. The drug is prescribed to women for hormonal problems.

Combining alcoholic drinks is completely contraindicated. If the drug and strong drinks are used together, you should drink more liquid.

When is Atarax prescribed?

The drug is recommended for patients to relieve:

withdrawal syndrome (hangover);
psychomotor tension;
anxiety;
pronounced neurosis-like state;
asthenia (chronic fatigue syndrome);
some mental illnesses, which are characterized by an increase in irritability.

Atarax also copes with the manifestations of skin itching, urticaria, dermatitis and eczema, acting as an antihistamine. The drug is prescribed in the preoperative period to prepare the patient for the effects of anesthesia, relieve anxiety and tension before surgery. Before you start taking Atarax, you need to consult a specialist!

What is the period of time between the consumption of an alcoholic drink and the medicine?

After drinking a strong drink, the medicine should be taken after ethanol is completely eliminated from the body. The waiting time depends on the strength of the drink, the maximum time is one and a half days. When can you drink alcohol if you have completed your course of therapy?

If a sedative and an alcohol-containing drink were taken together once or twice, such an act will not cause much harm to health. But there is no need to take risks; there is no beneficial interaction between the sedative medication and alcohol.

Organs affected by the toxin

The combined use of pharmacological agents and alcohol has a toxic effect on the internal organs and environments of the body. Alcohol, entering into a chemical reaction with a medicine, leads to poisoning, disrupts physiological processes, enhances or weakens the healing properties of drugs.

The liver suffers more than other organs. She gets hit twice. Many medications have a side effect - hepatotoxicity, destroy cells, and disrupt the physiology of the organ. In the liver, alcohol breaks down to ethanal, a substance 20-30 times more toxic than ethanol, which causes the death of hepatocytes.

Dangerous groups of drugs for organs in combination with alcohol:

Anti-inflammatory;
Hormonal;
Antibacterial;
Antifungal;
Glucose control agents for diabetes mellitus;
Antituberculosis;
Cytostatics (chemotherapy drugs);
Tranquilizers (anti-epileptic, psychotropic).

In second place among the internal organs exposed to the harmful effects of alcohol together with medications is the heart and vascular system. Strong drinks during drug therapy constrict blood vessels and increase blood pressure. The simultaneous intake of alcohol and chemical substances leads to failure of the myocardium and increases the risk of developing an attack of angina pectoris and a heart attack.

Health and treatment

The content of the article:

B Carbamazepine (text) ⇒ Bromodihydrochlorophenylbenzodiazepine (found)

Basic interactions (Carbamazepine)

Incompatible with MAO inhibitors. Increases the hepatotoxicity of isoniazid. Reduces the effects of anticoagulants, anticonvulsants (hydantoin derivatives or succinimides), barbiturates, clonazepam, primidone, valproic acid. Phenothiazines, pimozide, thioxanthenes increase CNS depression; cimetidine, clarithromycin, diltiazem, verapamil, erythromycin, propoxyphene reduce metabolism (the risk of toxic effects increases). Reduces the activity of corticosteroids, estrogens and estrogen-containing oral contraceptives, quinidine, cardiac glycosides (induction of metabolism). In the presence of carbonic anhydrase inhibitors, the risk of osteogenesis disorders increases.

Interactions from trade names (Tegretol CR)

The CYP3A4 isoenzyme is the main enzyme responsible for the formation of carbamazepine-10,11-epoxide. Concomitant use of CYP3A4 inhibitors with Tegretol CR may lead to increased plasma concentrations of carbamazepine, which, in turn, may cause side effects. The combined use of CYP3A4 inducers may lead to an acceleration of the metabolism of Tegretol CR and, thus, to a possible decrease in the plasma concentration of carbamazepine, and therefore to a possible decrease in the severity of the therapeutic effect. Discontinuation of concomitantly taken CYP3A4 inducers may reduce the rate of biotransformation of carbamazepine and, as a result, lead to increased plasma levels of carbamazepine. The level of carbamazepine in plasma can be increased by verapamil, diltiazem, dextropropoxyphene, viloxazine, fluoxetine, fluvoxamine; possibly - cimetidine, acetazolamide, danazol, desipramine, nicotinamide (in adults, only in high doses); nefazodone, macrolide antibiotics (eg, erythromycin, troleandomycin, josamycin, clarithromycin); azoles (for example, itraconazole, ketoconazole, fluconazole), terfenadine, loratadine, viral protease inhibitors (for the treatment of HIV infection, for example, ritonavir). Since an increase in carbamazepine plasma levels may lead to side effects (for example, dizziness, drowsiness, ataxia, diplopia), in these situations the dose of Tegretol CR should be adjusted and/or carbamazepine plasma levels should be regularly monitored. Plasma carbamazepine levels may be reduced by phenobarbital, phenytoin, primidone, progabide or theophylline, methsuximide, phensuximide, rifampicin, cisplatin or doxorubicin and, although the data are partially conflicting, possibly also clonazepam, valproic acid or valpromide, oxcarbazepine, herbal preparations containing St. John's wort (St. John's wort). Hypericum perforatum). On the other hand, there are reports that valproic acid, valpromide and primidone increase the plasma concentration of the pharmacologically active metabolite, carbamazepine-10,11-epoxide. Therefore, dose adjustment of Tegretol CR may be required. When administered concomitantly with felbamate, a decrease in the serum concentration of carbamazepine is possible, associated with an increase in the concentration of carbamazepine epoxide, while a decrease in the serum concentration of felbamate is possible. Isotretinoin has been reported to alter the bioavailability and/or clearance of carbamazepine and carbamazepine-10,11-epoxide; in this case, monitoring of carbamazepine plasma concentrations is required. Carbamazepine may reduce plasma concentrations or reduce or even completely eliminate the effects of some drugs. Dose adjustments of the following drugs may be required: clobazam, clonazepam, ethosuximide, primidone, valproic acid, alprazolam; corticosteroids (eg, prednisolone, dexamethasone); cyclosporine, digoxin, doxycycline, felodipine, haloperidol, imipramine, methadone, oral contraceptives (selection of alternative methods of contraception is necessary), theophylline, oral anticoagulants (warfarin, phenprocoumon, dicumarol), felbamate, lamotrigine, zonisamide, tiagabine, topiramate, tricyclic antidepressants ( for example, imipramine, amitriptyline, nortriptyline, clomipramine), clozapine, oxcarbazepine, protease inhibitors used in the treatment of HIV infection (indinavir, ritonavir, saquinavir), calcium channel blockers (dihydropyridine group, for example, felodipine), itraconazole, levothyroxine, midazolam, olanzapine, drugs containing estrogens and/or progesterone, praziquantel, risperidone, tramadol, ciprasidone. There are reports that while taking carbamazepine, the level of phenytoin in the blood plasma may either increase or decrease, and the level of mephenytoin may increase (in rare cases). When carbamazepine and paracetamol (acetaminophen) are used together, the bioavailability of the latter may decrease. There are reports of increased hepatotoxicity caused by isoniazid in cases where it was used concomitantly with carbamazepine. The combined use of carbamazepine and lithium or metoclopramide, as well as carbamazepine and antipsychotic drugs (haloperidol, thioridazine) can lead to an increase in the frequency of adverse neurological reactions (in the case of the latter combination, even with therapeutic concentrations of active substances in the blood plasma). The simultaneous use of Tegretol CR with some diuretics (hydrochlorothiazide, furosemide) can lead to hyponatremia, accompanied by clinical manifestations. Carbamazepine may antagonize the effects of non-depolarizing muscle relaxants (eg, pancuronium). If such a combination of drugs is used, it may be necessary to increase the dose of these muscle relaxants; Patients should be closely monitored as the effects of muscle relaxants may cease more quickly than expected. Bleeding has been reported in women between menstrual periods when oral contraceptives were used at the same time. The drug may reduce the therapeutic effect of oral contraceptives due to the induction of microsomal enzymes. Carbamazepine, like other psychotropic drugs, can reduce alcohol tolerance. In this regard, the patient is advised to stop drinking alcohol. Coadministration with grapefruit juice may increase plasma levels of carbamazepine.

B Bromodihydrochlorophenylbenzodiazepine (text) ⇒ Carbamazepine (found)

Basic interactions (Bromdihydrochlorphenylbenzodiazepine)

Strengthens (mutually) the effect of neuroleptics, tranquilizers, sleeping pills, anesthetics, analgesics, anticonvulsants, alcohol.

Interactions from trade names (Phenorelaxan)

Phenorelaxan is compatible with other drugs that cause depression of the central nervous system (hypnotics, anticonvulsants, antipsychotics, etc.), however, when used in combination, it is necessary to take into account the mutual enhancement of their effects. Reduces the effectiveness of levodopa in patients with parkinsonism. May increase the toxicity of zidovudine. Microsomal oxidation inhibitors increase the risk of toxic effects. Inducers of microsomal liver enzymes reduce effectiveness. Increases the concentration of imipramine in the blood serum. Antihypertensive drugs may increase the severity of the decrease in blood pressure. Increased respiratory depression may occur during concomitant administration of clozapine. Additionally for tablets. There is a mutual enhancement of the effect with the simultaneous administration of central muscle relaxants, narcotic analgesics, and ethanol.

Rules for taking medications and alcohol

Drinking alcohol during treatment minimizes the clinical effect of therapy and creates a risk of developing complications of the disease.

If this cannot be avoided, follow the rules of behavior that will reduce the consequences:

Do not drink strong drinks (vodka, cognac, whiskey), choose dry wine (100-150 ml), beer (no more than 300 ml). Don't drink alcohol on an empty stomach.
The interval between doses should be at least 2 hours.
To reduce the toxic effect, take medications that protect the liver (hepatoprotectors), pancreas (pancreatin), and stomach (antacids ─ Rennie, Almagel).

If a person takes antiviral medications for colds, anti-inflammatory drugs, alcohol in moderation does not pose a threat to the body.

Alcoholic drinks during treatment are contraindicated in cases of liver cirrhosis, severe infectious diseases, and during a course of chemotherapy.

Medicines, alcohol and chronic diseases

If a person has chronic diseases, simultaneous use of alcohol and medications is potentially dangerous for the functioning of vital organs. Since patients systematically take prescribed medications, the influence of alcohol can lead to negative consequences.

People with chronic heart disease (angina pectoris, heart defects) develop arrhythmias of varying severity. Heart attacks with severe pain syndrome develop, which is not relieved by Nitroglycerin, and the risk of developing myocardial infarction increases significantly.

In case of chronic liver diseases (viral hepatitis, hepatosis), alcohol during treatment will become a trigger in the development of cirrhosis and hepatocellular carcinoma (cancer).

Drinking alcohol during cirrhosis leads to the following consequences:

Bleeding into the abdominal cavity;
Liver decomposition, infection, peritonitis;
Hepatic coma;
Death.

If a person is on long-term treatment with sedatives, psychotropic drugs, tranquilizers, he is contraindicated in drinking alcohol. This leads to severe depression and the appearance of obsessive states (hallucinations, phobias). Suicidal feelings develop. The patient needs constant monitoring and assistance from a psychiatrist.

What side effects may the drug have?

Impact on the nervous system. The main side effect quite often noted by patients is drowsiness. In addition, there was a headache and some lethargy. Dizziness, insomnia, and hand tremor (shaking) did not occur very often. Quite rarely, patients reported seizures.
Impact on the psyche. Increased excitement is possible. Hallucinations and loss of orientation in space rarely occurred.
Effect on the cardiac system. Sometimes there was an increase in heart rate - tachycardia.
Tachycardia
Effect on the respiratory system. Bronchospasm rarely occurred.
Effects on the gastrointestinal tract. A fairly common phenomenon noted after taking Atarax tablets is dry mouth. Patients rarely reported nausea. Vomiting and constipation were rarely observed.
Effect on the urinary system. Urinary retention was rarely observed.
Effect on the immune system. Cases of anaphylactic shock have occurred very rarely.
Effect on the vascular system. Atarax may lower blood pressure.
Impact on general well-being. You may feel tired and unwell.

Due to some side effects, such as drowsiness, fatigue, you should not drive or operate complex machinery while taking Atarax.

The most dangerous combinations and consequences

The combination of alcohol and chemical-based drugs leads to serious disorders in the body, and sometimes to fatal consequences.

List of medications and their side effects in combination with alcohol:

Checking the compatibility of the drugs Afobazol and Donormil. Is it possible to take these medications together and combine their intake?

No interaction detected.

Interacts with the drug: Afobazole

When taking the drug Donormil ® simultaneously with sedative antidepressants (amitriptyline, doxepin, mianserin, mirtazapine, trimipramine), barbiturates, benzodiazepines, clonidine, morphine derivatives (analgesics, antitussives), neuroleptics, anxiolytics, sedative antihistamines, central antihypertensive drugs, thalidomide, Baclofen and pizotifen enhance the inhibitory effect on the central nervous system.

The check was carried out using the database of drug reference books: Vidal, RLS, Drugs.com, “Medicines. A manual for doctors in 2 parts,” ed. Mashkovsky M.D. The idea, grouping and selective manual analysis of the results were carried out by candidate of medical sciences, general practitioner Pavel Mikhailovich Shkutko.

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All combinations, comparisons and other information presented on the site are reference information generated automatically and cannot serve as a sufficient basis for making decisions on treatment tactics and disease prevention, as well as the safety of using drug combinations. A doctor's consultation is required.