Noofen and Phenibut, the difference between drugs

1. Phenibut or Anvifen?
2. Reviews from doctors
3. Where can I buy?

Phenibut and Anvifen are drugs that do not differ in their effects on the body.
They are analogues of each other. The composition of both drugs is based on aminophenylbutyric acid. Their effect is aimed at stabilizing the functioning of the central nervous system by normalizing the metabolism of its tissues. It is a mistake to believe that these are two drugs with completely similar composition. Auxiliary components may differ, but the effect on the body is the same.

The following drugs are prohibited:

• people suffering from liver diseases;
• for those who have individual intolerance to elements in the composition of the drug;
• pregnant women, women during lactation;
• children under three years old;
• people with diseases of the gastrointestinal tract.

There are discrepancies (subjective opinions) in side effects. Phenibut has more of them: drowsiness, nausea, causeless anxiety, nervous agitation, allergic reactions, headaches; Anvifen only causes drowsiness.

General characteristics of the drug

The drug "Phenibut" was created in the Soviet Union in the 70s of the 20th century. It was developed as a treatment for children with behavioral disorders. But it turned out that it has many beneficial properties. It can be used for chronic stress, neuroses, depression, and sleep disorders. Phenibut is also effective for cerebrovascular accidents, encephalopathy, decreased concentration, and dizziness. It is prescribed for menopausal syndrome, enuresis, withdrawal syndrome, and increased fatigue.

This effectiveness is associated with the composition of the drug. Its main active ingredient is aminophenylbutyric acid. It is a derivative of phenylethylamine and gamma-aminobutyric acid, which plays a leading role in human brain activity. This substance improves nerve conduction between neurons in the brain. In addition to the main active ingredient, the drug contains the usual auxiliary components. This product is available in 250 mg tablets.

List of analogues

Popular analogues:

• Afobazole – helps with stress, anxiety, disturbed sleep, improves adaptation and is used in the complex treatment of other nervous diseases;
• Tenoten is a homeopathic drug that eliminates the symptoms of psychotic and neurotic conditions, and is additionally used in the treatment of skin diseases and hypertension;
• Stresam is a registered drug of stronger action with pronounced side effects;
• Phenibut and Anvifen;
• Adaptol;
• Picamilon - used to improve attention and memory, in the treatment of migraines and headaches.

Analogues in Ukraine of Noofen are practically no different from the medicines presented in Russia.

• The online medical service is designed to select the optimal replacement for medications.
• Find cheap analogues for expensive drugs.
• For drugs that do not have complete analogues, look at the list of drugs that are most similar in use.
• If you are a professional, then the help of artificial intelligence will help you select treatment.

The drug “Phenibut” has: 5 complete analogues, the cheapest is Anvifen (203-431ք); 100 analogues in action, the most similar is Phenazepam (89-173ք)

It is not recommended to self-medicate with generics without a prescription from a specialist, since incorrect and inappropriate use leads to negative consequences. Commonly used over-the-counter Phenibut substitutes include:

1. Adaptol is part of a group of drugs with an anxiolytic effect. Both Phenibut and its analogue with this name reduce anxiety, relieve fears, and reduce excitability. Adaptol will eliminate neurosis or irritation and relieve emotional tension. It significantly increases brain performance and improves memory. Like other over-the-counter Phenibut analogues, Adaptol treats sleep problems.
2. Vinpocetine is taken for neurology and is often prescribed for the treatment of forms of cerebrovascular abnormalities, therapy after a stroke, vascular dementia, and various types of encephalopathy. The drug weakens mental symptoms.
3. Afobazole is an analogue prescribed to combat mental disorders. Afobazole relieves headaches, cramps, eliminates increased sweating and insomnia. This is a similar analogue of Phenibut in composition.
4. Pantogam is prescribed for serious disorders. The indications for the drug are as follows: traumatic brain injury, schizophrenia, atherosclerotic vascular degradation, syndromes caused by neuroleptic effects, epileptic seizures, mental retardation of various levels. This is a potent drug similar to Phenibut. It is not advisable to resort to treatment with the drug without a medical prescription.
5. Cortexin is most often used in the treatment of problems with cerebral circulation, cranial injuries, encephalitis, paralysis, and developmental delays.
6. Piracetam is a traditional remedy known for its mild effects and is approved for children. Psychiatric practice involves the use of Piracetam for neurotic conditions and hypochondriacal disorders. Fights schizophrenic conditions. It can be used to improve well-being and increase the level of brain activity.

Diseases for selection

Doesn't interact with

Add diseases and medications so that the Cyberis artificial intelligence selects analogues that do not have dangerous contraindications or interactions with the drug administered.

Note! The list contains synonyms for Aminophenylbutyric acid, which have a similar composition, so you can choose a replacement yourself, taking into account the form and dose of the medicine prescribed by your doctor. Give preference to manufacturers from the USA, Japan, Western Europe, as well as well-known companies from Eastern Europe: KRKA, Gedeon Richter, Actavis, Egis, Lek, Hexal, Teva, Zentiva.

Popular analogues of the drug:

1. Selank. This drug is in the form of drops. This remedy has an anti-anxiety, anxiolytic effect on the body. It is used to improve brain function, increase activity, performance, improve memory, and eliminate sleep disorders.
2. Tranquesipam. This is a drug that has anxiolytic, sedative-hypnotic, anticonvulsant and central muscle relaxant effects. Available in the form of tablets and solution for intramuscular and intravenous administration. It is used for neurotic, neurosis-like, psychopathic, psycho-like conditions. Helps relieve fatigue, emotional stress, fear, headaches, helps with sleep disorders, frequent nightmares.
3. Elzepam. This drug has a sedative, anxiolytic, anticonvulsant, hypnotic and muscle relaxant effect. Helps eliminate various neurotic conditions, autonomic disorders, sleep problems, relieves fatigue, tension and irritability.
4. Strezam. The drug belongs to a group of drugs that have sedative and anxiolytic effects. It is prescribed to eliminate feelings of anxiety, fear, apathy, to eliminate autonomic disorders, internal tension and increased irritability.
5. Phenazepam is a psychotropic drug that suppresses feelings of anxiety, fear, anxiety, and also relieves emotional stress. Belongs to the group of anxiolytics.
6. Afobazole is an anxiolytic. This remedy is intended to eliminate various mental disorders, to eliminate feelings of fear, anxiety, and strong emotional stress. It is often prescribed to relieve autonomic disorders, namely headaches, dizziness, frequent muscle twitching, increased sweating, to eliminate sleep disorders and insomnia.
7. Anvifen. This remedy has nootropic, antiplatelet, antioxidant, tranquilizing and anticonvulsant effects. Prescribed for the treatment of anxiety-neurotic and asthenic disorders, enuresis, stuttering, nervous tics in childhood. In addition, it helps eliminate anxiety, sleep problems and insomnia, and dizziness that arise due to dysfunction of the vestibular apparatus.
8. Noofen. This drug has a psychostimulating, tranquilizing, nootropic effect. It is prescribed during asthenia to improve performance without side effects, namely increased excitability or irritability. In addition, it is prescribed to patients who have vasovegetative symptoms - headaches, rapid mood swings, sleep problems, insomnia, dizziness.
9. Tenoten. This is a homeopathic type drug. It has an antidepressant, anti-anxiety, and anti-asthenic effect on the body. This remedy strengthens the central nervous system, improves memory, and increases concentration. In addition, the medicine is prescribed for severe irritability, neurotic conditions, psychosomatic disorders, as well as for feelings of causeless anxiety.
10. Adaptol. This is a medicine that belongs to the group of drugs with anxiolytic effects. Helps relieve feelings of fear, anxiety, increased excitability, eliminates neuroses, irritation, and emotional stress. Improves brain performance, increases mental abilities and memory. In addition, it is used to treat sleep disorders and insomnia.
11. Mebicar. This remedy has a stress-projective, anxiolytic, nootropic effect. While taking this drug, the oxygen supply to myocardial tissue improves, and the plasma electrolyte balance and potassium content in the blood, red blood cells, and myocardial tissue are regulated. Helps with coronary heart disease, cardialgia and various neurotic disorders.

Different

Your doctor can advise which drug is best to choose. It is not for nothing that neurologists, when prescribing Phenibut, recommend purchasing the Latvian drug, although it is more expensive. In addition to this manufacturer, the drug is produced in Belarus and in three pharmaceutical companies in Russia. The drug is produced in all five factories from the same active ingredient and using the same technology. But the quality of these medicines is different.

• If you look at which manufacturer of Phenibut is better to choose, reviews note that the Latvian drug is the highest quality. This is due to strict control over all stages of production. The drug is produced from high-quality raw materials and meets quality standards adopted in the EU and the USA.
• In second place are drugs from Russian manufacturers. If you choose among them which is better, the reviews call JSC "Obninsk Chemical-Pharmaceutical Ozone".
• All reviews give third place to drugs produced in the Republic of Belarus and OJSC Organika.

Contraindications

The use of Phenibut with increased caution is largely due to the existing contraindications, although their list is very small:

• First of all, this is the period of bearing a child and breastfeeding.
• Hypersensitivity to the drug, individual intolerance to its components.
• Presence of acute renal failure.
• Irritant effect of Phenibut on the mucous layers of the gastrointestinal tract.
• Risk of developing negative side effects.
• The possibility of developing dependence when using Phenibut in large doses during self-medication.
• The appearance of withdrawal syndrome.

With prolonged use of the drug, the doctor monitors liver function indicators and the results of a clinical blood test. Taking pills can provoke acute intoxication and the appearance of various negative symptoms, including falling into lethargy.

For those who take the medicine for a long time, an increased danger is the possibility of developing an addiction syndrome, and abrupt withdrawal of the medicine often leads to withdrawal symptoms, the symptoms of which are:

• restlessness and agitation;
• loss of appetite;
• chronic fatigue;
• loss of sleep;
• dizziness;
• nausea with vomiting attacks;
• depressive states;
• cognitive impairment;
• tremor;
• cardiopalmus;
• psychotic symptoms, including delusions, auditory and visual hallucinations.

A prescription for the drug is issued only if there are no contraindications, and it must be certified by the doctor’s signature and seal. The second person signing the prescription is the head physician of the medical institution.

Reasons for poor quality

Why does the question arise, which is better? Reviews note that some drugs are more likely to cause side effects and are less effective. This is due to the quality of the raw materials and the production itself. Some unscrupulous manufacturers purchase raw materials at reduced prices - those that are about to expire. In addition, most Russian pharmaceutical companies purchase raw materials in India and China, where a license is not required to confirm its quality.

This is also due to the manufacturing technology of the drug. Russian and Belarusian factories do not always use modern equipment. In addition, the manufacturing technology may be violated. After all, before you put the components of a new drug into a container, it needs to be properly cleaned, which is not always done. Therefore, medications may contain unnecessary impurities.

Why did you become a prescription?

The drug was no longer sold in pharmacies without a prescription in 2020, and this may seem quite strange, given the fact that it is prescribed even to children and the drug is not classified as a narcotic substance. However, it has been proven that uncontrolled use of this sedative drug contributes to the development of addiction; therefore, the duration of therapy should be determined by a medical professional to avoid problems. And precisely to eliminate the risk of overdose and use of the substance without any control, Phenibut was included in the list of drugs that pharmacies must dispense exclusively by prescription.

Even though it is not a drug in the full sense of the word, Phenibut is able to enhance the effects of drinks containing alcohol, regardless of its quantity. After taking the pills, even ordinary beer can provide increased sensations and pleasure that is not typical of reality. Considering the incompatibility of Phenibut with alcohol and in order to prevent the spread of drug addiction - and especially among young people - its distribution in the pharmacy network is carried out only by prescription.

The validity period of the prescription is based on the condition of the victim and the pathological processes present and is most often one month. In some cases, the period can reach one year.

Results of using the drug

Phenibut is really effective. All doctors who prescribe this drug note that patients quickly improve. They become calmer and sleep better. In addition, when taken correctly, the following treatment results are observed:

• memory improves;
• the stability of the nervous system increases;
• depression decreases;
• negative emotions are smoothed out;
• excitability and irritability disappear;
• sleep quality improves;
• performance improves.

Reviews from doctors about Phenibut

It's hard to say which manufacturer is better. If we consider the safety and effectiveness of the drug, we can note the Latvian production. All doctors note that it is when taking this drug that the result is observed, as stated in the instructions. In addition, side effects are very rare. But reviews of Phenibut do not always focus on this. Some people determine which manufacturer is better based on price. And the Latvian drug costs almost 2 times more than the Russian one. Therefore, some consumers buy Phenibut for 200-250 rubles, despite the fact that its quality is lower.

How to use?

To avoid negative reactions to taking Phenibut, you must follow the dosage. Adult patients take tablets three times a day in the amount of 250 mg once. If a single dose does not give the expected effect, it can be increased to 750 mg. The maximum amount of Phenibut taken per day by persons over 60 years of age does not exceed 1.5 g. For those whose age is less than 60 years, the daily dose reaches 2.5 grams.

When treating children under eight years of age, the amount of Phenibut per day is up to 0.3 grams. If the child is between 8 and 14 years of age, he is prescribed an adult dose of 250 mg, taken three times a day.

The duration of treatment usually does not exceed 2-3 weeks, but this period can be increased to 1.5 months. If the treatment course needs to be repeated, the pause between doses should be from 2 to 4 weeks.