PIRACETAM or MEXIDOL: which is better and what is the difference (differences in composition, reviews from doctors)

Ceraxon or Cerebrolysin, which is better?

Prices for the drug CERAKSON
Name: Goldie-88 Review: Like many people, we were prescribed the drug Cerakson by a neurologist. The baby is 4 months old, at the end of pregnancy we had slight hypoxia. Because of this, the baby does not sleep very well and often wakes up. Before this, we already drank Pantogam syrup and the drug Gliatilin.

The drug Ceraxon is intended to improve cerebral circulation. It is a solution for oral administration. It is clear in color and has a strawberry scent. You need to measure it using a measuring syringe. We give medicine to the child from it. We were prescribed to drink it 2 times a day, 0.5 ml.

Be sure to take it before 18:00, as if you take it later, you may have problems sleeping at night. The baby drinks it well, I think because it is sweet) Now about the effect. I didn’t expect it, but our sleep improved almost immediately! Previously, the child did not sleep at all during the day, rarely, but now he began to sleep 2-3 times.

Night sleep also became longer, and most importantly, stronger. The child is active, cheerful, I think this is because he finally began to get enough sleep) There was one drawback: after a month of treatment, the baby began to be very capricious in the evenings. I think this is due to the fact that we did not always accurately measure 0.5 ml, sometimes we gave more.

But a month has just passed and we finished drinking Cerakson. The whims immediately ended, but healthy sleep remained.

Reviews

Anastasia, patient: “On the doctor’s recommendation, I took Piracetam for a month. I needed it to reschedule the session. The positive effect of the medicine is noticeable immediately. Improves attention, memory, and overall performance. Against this background, stress is felt less. I’m pleased with the price and availability of the drug.”

Maxim, patient: “I took Piracetam for vascular dystonia. Within a month and a half, the headache and dizziness went away.”

Natalya: “I took Mexidol to treat an anxiety disorder. But the doctor prescribed it to me in combination with other medications. It was assumed that Mexidol would enhance their effect. And so it happened. I didn’t notice any side effects.”

Elena Viktorovna, psychiatrist: “If a client complains of stress, fatigue, overload, then I prescribe Piracetam. And if you have to deal with brain injuries, circulatory disorders, mental pathologies, then Mexidol. More often I prescribe an injectable form of the medicine. Side effects sometimes include dry mouth and cephalalgia.”

Cerebrolysin or Cortexin – which is better for adults and children

Cortexin is a cheaper analogue of Cerebrolysin in ampoules, also obtained from pig brain. Available in powder, dissolved in sodium chloride, water or novocaine before use. The drug is administered intramuscularly once a day, for severe lesions - twice a day. Is a painful injection.

Cerebrolysin substitute has similar effects. The medicine improves cognitive function, improves metabolism in damaged brain tissue and protects cells from destruction and adverse factors, accelerates the synthesis of peptides and metabolic processes. Restrictions on use include pregnancy and individual intolerance to the components.

Cerebrolysin is a similar drug in the form of ampoules ready for administration. It has the same therapeutic effects as Cortexin. Has positive reviews from doctors.

What is the difference between the two analogues:

The cost of Cortexin is lower.
Cerebrolysin is not used for status epilepticus and acute renal failure; in this case, Cortexin is the drug of choice.
For children and adults with mild brain damage, Cortexin is recommended; for severe conditions, Cerebrolysin is more often prescribed.

Which is better, Cortexin or Cerebrolysin, depends on the severity of the patient’s condition, indications, history of contraindications, and financial capabilities.

Doctors' opinion

Vasily Igorevich, neurologist

In my practice, I often prescribe Mexidol and Piracetam together, but I only warn that the second drug should be taken in the morning, because... Insomnia may occur. If all recommendations are followed, the effectiveness of the product increases and the treatment period is reduced.

Alevtina Igorevna, psychiatrist

Piracetam is often prescribed to treat Alzheimer's disease. It helps improve brain activity and normalize its functions. During therapy, it is necessary to strictly adhere to the dosages prescribed by the doctor.

Which one is better, when and for whom?

Ceraxon cannot be prescribed for the treatment of patients under 18 years of age, unlike Cerebrolysin, which can be used in pediatrics; also, according to indications, the latter can be used by women who support breastfeeding.

When prescribing Ceraxon during lactation, the baby must be switched to an adapted formula.

If a person drives a car or works in production where a high reaction speed is required, then it is better to give preference to Cerebrolysin, since it does not have a negative effect on the ability to drive a car. During treatment with Cerakson, care must be taken when driving vehicles and performing work that requires good reaction speed.

Cerebrolysin should not be prescribed if the patient has the following pathologies:

Epistatus.
Acute renal failure.

You should refrain from treatment with Cerakson if the following deviations from the norm are found:

Severe vagotonia, in which the parasympathetic nervous system predominates.
The oral solution should not be taken by patients who have an intolerance to fruit sugar.

If the patient receives drugs based on meclofenoxate, then he cannot be prescribed Ceraxon; in this case, it is better to give preference to Cerebrolysin.

It is impossible to say clearly which drug Cerebrolysin or Ceraxon is better, since each drug has its own contraindications and any of them can cause a number of side effects. If the patient has no one to give injections, then it is better to choose Ceraxon in the form of an oral solution. Children and nursing women should give preference to Cerebrolysin.

It must be remembered that both nootropics are available with a doctor’s prescription and self-medication with them is unacceptable; only a specialist can assess the severity of the pathological process and select an adequate treatment regimen.

Cereton or Ceraxon, which is more effective?

Reviews from doctors who use gliatilin and Cerepro to treat patients indicate the high effectiveness of both drugs.

Both drugs are central cholinergic stimulants, which contain 40.5% metabolically protected choline. When the drug enters the body, it is broken down by enzymes into choline and glycerophosphate.

Choline takes part in the biological synthesis of acetylcholine, one of the mediators of nervous excitation.

Glycerophosphate is a precursor to neuronal membrane phospholipids. It has the following effects:

Provides the synthesis of acetylcholine and phosphatidylcholine in neuronal membranes;
Improves blood flow and enhances metabolic processes in the central nervous system;
Activates the reticular formation;
Increases the linear speed of blood flow on the side of the traumatic brain injury;
Helps normalize the spatiotemporal characteristics of spontaneous bioelectrical activity of the brain;
It has a positive effect on the cognitive and behavioral reactions of patients suffering from vascular diseases of the brain.

Glycerophosphate improves brain function by influencing factors in the development of involutional psychoorganic syndrome, changes the phospholipid composition of neuronal membranes and increases cholinergic activity.

Depending on the dose used, it stimulates the release of acetylcholine, improves synaptic transmission, plasticity of neuronal membranes and receptor function.

Does not affect the reproductive cycle, does not cause mutations or malformations of the fetus.

Gliatilin is an original drug that is produced in Italy. Its main active ingredient, choline alfoscerate, protects against brain cell damage. The cost of 14 capsules, which contain the same 400 mg of active substance, starts from 717 rubles. Doctors at the Yusupov Hospital decide what to prescribe, Gliatilin or Cerepro, together with patients and their relatives.

How they affect the body

To determine which medication is better to use - piracetam or Mexidol, you need to familiarize yourself with the effects of each of them on the body.

Piracetam

Piracetam is a chemical nootropic drug, the use of which is practiced by psychotherapists, neurologists and narcologists. This is a medicine from a group of drugs to improve blood circulation and brain metabolism. The purpose of the medication is to protect and regenerate brain activity damaged as a result of intoxication and lack of oxygen supply.

Piracetam is needed for:

osteochondrosis;
dyslexia;
cortical myoclonus;
psychoorganic pathology;
attacks of headaches;
dizziness.

Mexidol

Mexidol is a nootropic drug of the latest generation. The medication is characterized by qualities that have a positive effect on brain functions. Under its influence in the body:

convulsive activity decreases;
toxic substances are eliminated from the body;
resistance to stressful situations increases.

A course of drug therapy can slow down the aging process of cells and get rid of depression. Since the medicine improves blood flow characteristics and serves as a catalyst for metabolism, it stabilizes blood circulation in the brain.

"cerakson". release form and composition

The nootropic drug is presented in the form of a colorless liquid with a characteristic odor. The main active ingredient is citicoline sodium.

Propyl parahydroxybenzoate, glycerol, potassium sorbate, citric acid, methyl parahydroxybenzoate, strawberry flavor, and purified water are used as auxiliary elements.

The medicine is intended for both internal use and injection.

Cicticolin, which is part of the drug, has a wide spectrum of action. Medicamen inhibits the action of phospholipase and restores damaged cells. Prevents the formation of free radicals.

The drug Ceraxon is most often included in complex therapy. Analogues can also be used together with other drugs. But you should not choose medications on your own.

The appointment must be made by a doctor.

The medicine is presented in the form of an amber-colored solution. The medicine is made on the basis of peptides obtained from pig brain. Sodium dioxide and purified water are used as auxiliary components. The Cerebrolysin solution is intended only for intramuscular administration. Injections are given in a medical facility.

The drug is based on low molecular weight neuropeptides that are able to penetrate the walls of nerve cells. The drug helps to increase the energy metabolism of the brain and significantly improves protein synthesis. Cerebrolysin solution is widely used as part of complex rehabilitation therapy after ischemic stroke.

As a preventative measure, the medications Ceraxon or Cerebrolysin can be prescribed. Injections help restore the patient’s normal well-being, normalize sleep, improve memory, and increase performance. Nootropic drugs are rarely used as monotherapy.

Contraindications

Piracetam can be used for the following conditions:

disturbances in mental activity and memory;
traumatic brain injuries (concussion, bruise);
atherosclerosis of blood vessels in the brain (a pathological condition accompanied by the deposition of fats on the walls of blood vessels, as a result of which the blood supply is disrupted);
addiction;
alcoholism;
senile dementia (memory loss);
schizophrenia and some other mental illnesses.

Mexidol can be taken for:

stress;
vegetative-vascular dystonia (a syndrome accompanied by impaired regulation of vascular tone and normal functioning of the nervous system);
coronary heart disease (a chronic disease in which the heart muscle cannot be sufficiently supplied with oxygen);
intoxication (alcohol, drugs and other poisons);
traumatic brain injuries;
anxiety disorder;
epilepsy.

Piracetam should not be used for:

kidney failure (a disease in which the kidneys cannot eliminate toxic substances);
drug intolerance;
up to 12 months of age.

Mexidol should not be used in the following conditions:

increased sensitivity;
liver or kidney failure;
age under 18 years;
period of pregnancy and breastfeeding.

Both drugs, in the form of a solution in ampoules for intravenous administration, are used to treat diseases of the cardiovascular system. But doctors often prefer intramuscular injections.

It is recommended to give injections at home after consulting a doctor. Headaches may be neurotic in nature and not a consequence of circulatory disorders in the vessels of the brain. In this case, you may be prescribed antipsychotic drugs.

Pregnant women are prohibited from taking medications together.

Childhood

Children should not use medications in any dosage form.

Elderly age

It is necessary to consult a doctor before starting therapy, especially if the patient has a chronic form of pancreatitis.

If hypersensitivity to active components is detected, medications should not be used.

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Mexidol is used to treat stroke, encephalopathy, VSD, myocardial ischemia, and glaucoma. The nootropic is necessary for the treatment of patients with ischemic stroke, in the case of the development of psychoorganic syndrome, Alzheimer's disease, and in patients with circulatory disorders.

The antioxidant is taken with caution by patients suffering from asthma. The dose of the nootropic drug is adjusted in patients taking blood thinning drugs.

Medicines are not used for hemorrhagic stroke, renal dysfunction, chorea, individual sensitivity, migraine.

The nootropic drug Piracetam was developed in the 60s. last century in Belgium. It was originally intended to treat seasickness. In subsequent years, a positive effect of the drug on brain function was revealed, manifested by:

increased resistance to hypoxia (oxygen deficiency);
stimulation of mental activity.

Piracetam served as the basis for the creation of a group of drugs called nootropics, used to improve cognitive abilities.

The active component of the drug is a cyclic derivative of GABA (gamma-aminobutyric acid), the main inhibitory neurotransmitter of the brain.

The effect of Piracetam is manifested:

At the cellular level – activates protein synthesis, restores the membranes of neurons and red blood cells, normalizes the functioning of membrane receptors.
In the body – improves the functioning of the central nervous system (CNS) and the state of the cardiovascular system during hypoxia.

Taking the drug helps eliminate the effects of hypoxia in brain tissue.

Taking the drug allows you to:

improve cognitive abilities - increase concentration, increase mental performance, enhance memory;
eliminate the effects of hypoxia in brain tissue;
increase the level of dopamine in the brain, a neurotransmitter necessary for mental activity;
regulate the content of serotonin in the cortex and other parts of the brain;
restore the functionality of red blood cells, reduce blood viscosity.

The drug is used to treat neurological symptoms in vascular parkinsonism, manifested by increased muscle tone, unsteadiness of gait, tremor, and slowness of movements.

Piracetam is included in treatment regimens:

Alzheimer's disease;
senile dementia;
coma;
osteochondrosis;
cortical myoclonus – lightning-fast muscle twitching;
migraine;
sickle cell anemia;
dizziness caused by vascular pathologies.

Nikolai Nikolaevich, 52 years old, Kazan

2 years ago I was diagnosed with disculatory encephalopathy. Piracetam and Mexidol were immediately prescribed. And last fall, instead of Piracetam, Phezam was prescribed, which added cinnarizine to piracetam.

The medications do not cause any unpleasant symptoms that are described in the instructions. At first there were fears that insomnia would appear.

Anna, 27 years old, Tambov

After the brain injury, I had severe headaches and dizziness. They prescribed Mexidol injections and Piracetam tablets.

It helped quickly. The headache has gone away, now my head hurts no more often than before the injury. And the dizziness completely disappeared.

Alexey Petrovich, 63 years old, Saransk

Mexidol and Piracetam were prescribed for hearing loss. In spring and autumn I undergo treatment with droppers, and then take pills for 2 weeks. Although the hearing has not been restored, it remains at approximately the same level and does not decrease. There is less noise in my head and I sleep better.

The instructions for use for Piracetam indicate that the drug is used for:

dementia,
comatose state of traumatic or vascular nature,
brain injury,
psychoorganic syndrome,
sickle cell anemia,
constant dizziness with imbalance.

It is used to treat children with learning disabilities that are not related to family relationships.

Mexidol is effective for:

acute disruption of blood flow in brain tissue,
traumatic brain injuries,
circulatory failure,
vegetative-vascular dystonia syndrome,
acute heart diseases.

Helps well with necrotizing pancreatitis or peritonitis.

Medicines should be used with caution if there is a history of allergies or bronchial asthma, impaired hemostasis or severe bleeding.

Nootropics should not be taken if:

impaired renal and liver function,
psychomotor overexcitation,
children under 1 year of age.

They are prescribed with caution when hemostasis is impaired.

Interaction with alcohol

The results of the studies indicate rare cases of adverse events (less than 1 case per 10,000 subjects).

Possible effects associated with exposure to citicoline include:

sleep disturbance;
dyspnea;
loss of appetite;
slight destabilization of the psycho-emotional background (apathy, agitation);
numbness felt in areas of paralyzed limbs;
loose stools;
vomit;
short-term change in blood pressure;
decreased activity of liver enzymes.

If there is hypersensitivity to certain substances, the body reacts characteristic of an allergy.

If side effects increase and your health condition deteriorates sharply, you should seek qualified medical help.

When selecting drugs for complex treatment, it should be taken into account that the active substance (citicoline) enhances the effect of levodopa.

Ceraxon should not be taken in combination with drugs containing meclofenoxate.

To minimize side effects and various complications, it is recommended to refrain from drinking alcoholic beverages during drug therapy. This is especially true for pregnant women (any trimester of pregnancy).

If unusual situations arise, a one-time combination of alcohol and drugs is possible, but drinks must be consumed in compliance with the following intervals:

syrup and solution – 24 hours for men, 32 hours for women;
injections – 15 days after completion of the course of treatment.

The consequences of ignoring the duration of breaks include heart rhythm disturbances, attacks of tachycardia, bradycardia, and orthostatic hypotension.

To relieve anxiety symptoms, you need to stop drinking alcohol and drink more water (especially the first 4-6 hours). If the condition worsens, you should seek qualified help.

Dosage

The drug "Ceraxon" is intended for internal use. Analogs can be used in a different mode. Therefore, you should consult your doctor first. The medication "Ceraxon" is taken with meals. It is recommended to dilute the required amount of the drug in a small amount of water.

The duration of the course depends on the individual characteristics of the patient, as well as the form of the disease.

The drug "Ceraxon" can also be used for intramuscular administration. The injection should be done slowly. This will avoid side effects such as dizziness and fever. In the acute period of ischemic stroke, 1000 mg of the drug is prescribed every 12 hours. As soon as clinical improvements are noticeable, you can switch to the oral form of the medication.

It is also worth using the drug “Cerebrolysin” correctly. Instructions, price, exact dosage - all this can be clarified with your doctor. A single injection of 50 ml is possible.

However, treatment with a course is more preferable. In the acute period of ischemic stroke, use 20-50 ml once a day. The exact dosage depends on the individual characteristics of the patient.

During the recovery period, 5-10 ml are prescribed.

Instructions for use

Actovegin is mainly used in small doses. The amount should not exceed 5 ml per day, since the medicine belongs to hypertonic solutions. Before administration, it is necessary to make a test injection to detect allergic reactions to the drug. In cases of severe condition of the patient, 10-20 ml of the drug per day is initially administered, later 5 ml is administered daily.

For administration via droppers, 10-40 ml of medication is added to 200-300 ml of isotonic glucose solution. This dropper is designed for 1-2 times, their frequency is determined by the patient’s condition. When treated during pregnancy, the dose is adjusted by the doctor.

The introduction of Mexidol should occur gradually. As a rule, 50-100 ml of medicine is diluted with 200 ml of sodium chloride and dripped 1-3 times. 800 ml per day is considered the maximum amount of medication for use. For emergency treatment, the drug is administered intramuscularly at 200-300 ml once a day, and treatment is continued with 100 ml 3 times a day for several weeks.

It is imperative to know how to use Mexidol and Actovegin together. Thus, when using them together, it is necessary to administer the drugs one at a time in order to avoid destruction of the chemical structure of the constituent substances and the manifestation of deviations in the functioning of the body.

Drugs in tablet form are used in the same way - one or two tablets three times a day for 2-6 weeks.

At the same time, Ceraxon and Mexidol are taken for the following diseases

A combination of drugs may be prescribed for:

Acute cerebrovascular accident, including those caused by traumatic brain injury.
Last stage pancreatitis.
Severe forms of varicose veins, atherosclerosis.
Diabetes mellitus.
Stroke.

Medicines can be used to restore the elasticity of brain cells and relieve the negative effects of radiation therapy.

Mexidol can be used to restore the elasticity of brain cells and relieve the negative effects of radiation therapy.

Similar medications

The previously described drugs have many analogues. One of these is Actovegin. This medicine is available in the form of an injection solution, as well as in the form of tablets and ointments. This medication is classified as expensive. It helps fight diseases associated with metabolic disorders.

An equally well-known analogue of drugs that improve blood circulation in the brain is Vinpocetine. Before starting use, you should read the instructions and consult with your doctor.

Sources:

Vidal : https://www.vidal.ru/drugs/mexidol__14744 GRLS : https://grls.rosminzdrav.ru/Grls_View_v2.aspx?routingGu >

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Background information on the drug Mexidol

Mexidol and Pentoxifylline/Trental. Mexidol and Cavinton/Vinpocetine, or Agapurin. Mexidol compatibility. Chronic cerebral ischemia, hypertension... Comprehensive treatment

We have already described the original Russian drug Mexidol in some detail. Mexidol is often used in the complex treatment of a number of diseases, successfully combined with other medications, including Piracetam, Cavinton and Trental .

This article will look at some of these cases.

Atherosclerosis and hypertension lead to CCI (chronic cerebral ischemia).

Surgery can solve this problem. Conservative treatment helps only at the initial stage of the disease. Complex treatment is used, which includes a number of drugs, including Mexidol, Trental, Cavinton, etc.

Parkinson's syndrome often develops against the background of vascular pathology . Syndrome

Piracetam as a medicine

This effective medication is prescribed to stabilize brain activity, as well as to treat certain diseases. It is allowed for both children and adults. If you want to use both Mexidol and Piracetam at once, it is not recommended to do this without a doctor’s prescription.

Piracetam is prescribed to produce a calming effect on the nervous system. According to the instructions, you can identify several symptoms for which the use of the medication is possible:

Dizziness and pain in the head.
Dyslexia.
Osteochondrosis and other spinal problems.
Psychoorganic syndrome.

If we talk about contraindications, there are few of them, but you need to remember all the information. These include:

A person is allergic to some component.
I already had problems with my heart.
Kidney problems.
Women who are pregnant or nursing infants.

The main difference between both drugs

Piracetam is a nootropic drug that improves cerebral blood flow, as well as dilates intracranial vessels and increases the quantitative composition of neurotransmitters in the organ. Mexidol is primarily an antioxidant that has nootropic properties. This medicine is aimed at fighting free radicals and clearing neuronal membranes of them.

This medication not only improves blood flow in the brain, but also effectively resists stress and overexcitation of the nervous system. Mexidol has anticonvulsant, antianxiety and antihypoxic effects.

The main difference between Piracetam is that this drug can be prescribed to children from one year of age.

Comparison and how they differ

Despite the fact that both medications belong to the same pharmacological group, there are differences between them:

Cerebrolysin and Ceraxon have different active and inactive components, which should be taken into account by patients prone to allergies.
Cerakson is sold not only in injections, but also in the form of a solution for oral administration.
Cerebrolysin has a wider range of applications; it is prescribed to patients suffering from Alzheimer's disease, mental retardation and hyperactivity in children, in combination with other drugs for depression that is not treatable with antidepressants.
Cerebrolysin should be stored at temperatures up to 25 degrees, ampoules for 5 years, bottles for 4 years from the date of release. Ceraxon, regardless of the release form, must be stored at an ambient temperature not exceeding 30 degrees, for 36 months from the date of release of the drug.

Both drugs can cause side effects. Treatment with Ceraxon may cause:

Feeling hot.
Hallucinations.
Heart rhythm disturbance.
Tachycardia.
Edema.
Increased activity of liver enzymes.
Numbness in paralyzed limbs.
Constipation.

Cerebrolysin may cause the following undesirable effects:

Aggression.
Impaired consciousness.
Epilepsy and seizures.
Pain in the neck, lower back, limbs.
Chills.
Collapse.
Impotence.
Indifference to what is happening.
Flu-like condition.
Depression.
Hyperventilation.
Itching, redness and burning at the injection site.

Comparison of drugs

Mexidol 0.125 No. 50 tab. costs 476 rubles. The same drug in ampoules of 0.05 ml, 2 ml No. 10 solution is sold for 530 rubles. Piracetam in tablets 400 mg – 132 rubles, in ampoules 5 ml No. 10 – 42 rubles.

Piracetam will cost 27-140 rubles.

The second type of medication costs from 292 to 559 rubles.

Piracetam is a classic nootropic drug that is prescribed for weakened memory and impaired blood circulation in the brain.

Mexidol is many times superior to Piracetam in its anti-ischemic and antihypoxic effects. The drug exhibits anticonvulsant and anti-anxiety activity, eliminates symptoms of alcohol intoxication, and improves liver condition.

Similarities

Both drugs enhance the effect of neuroleptics. The use of Mexidol or Piracetam for the treatment of Parkinson's disease allows you to reduce the dose of the main drugs, which helps reduce the drug load and toxic side effects.

Both drugs increase the brain's resistance to hypoxia and the toxic effects of barbiturates and alcohol.

What is the difference?

Piracetam is prescribed as a nootropic – a drug that helps restore nerve cells and brain performance. Mexidol, in addition to nootropic activity, exhibits antioxidant and antihypoxic properties.

Mexidol is a fast-acting drug. The effect of using the nootropic Piracetam, manifested in improving cerebral blood supply, develops within 2 months of regular use.

This is due to the fact that Mexidol is a relatively new drug. There is not enough reliable information on how it will act on the child’s body.

Which is cheaper?

When choosing between Mexidol and Piracetam, you need to consider:

duration of treatment;
cost of medicines.

The course of therapy with Mexidol ranges on average from 2 weeks to 2 months, and when treated with Piracetam - from 2 weeks to 6 months.

Mexidol is more expensive, but the effectiveness of the drug is higher, and the course of treatment is shorter.

Cerakson

A nootropic drug intended for the treatment of sensory and motor neurological disorders of a degenerative and vascular nature. Prevents the death of brain cells and promotes the regeneration of damaged cell membranes. Inhibits the action of phospholipase.

In case of stroke, it reduces the volume of affected brain tissue, improves the transmission of impulses. In case of cranial stroke, it reduces the duration of coma and the recovery period.

Helps treat cognitive disorders such as loss of memory and attention, deterioration of speech and difficulties in performing habitual activities.

Has a moderate antioxidant effect.

Active ingredient: citicoline.

Release form: solution for intramuscular and intravenous administration, solution for oral administration.

Ceraxon contains citicoline as an active component, which has a wide spectrum of action:

Participates in the process of restoration of damaged cell membranes.
Blocks the appearance of free radicals and prevents cell death.
Suppresses the action of phospholipases, which can negatively affect mucous membranes.
With the development of a stroke, it reduces the degree of damage to brain tissue and improves the transmission of excitation in cholinergic synapses.
In patients with traumatic brain injury, treatment with the drug reduces the duration of post-traumatic coma and recovery period, and makes neurological symptoms less pronounced.
In case of chronic oxygen starvation, due to nootropic therapy, attention and self-care skills improve, and signs of amnesia are weakened.

Indications for use:

Acute period after ischemic stroke (as part of complex therapy).
Recovery period after ischemic and hemorrhagic stroke.
Traumatic brain injuries and the recovery period after them.
Behavioral and cognitive dysfunctions in brain lesions.

Cannot be used in case of individual intolerance to components, severe vagotonia, fructose intolerance, or under the age of 18 years. During pregnancy, it can be taken according to strict indications and provided that the benefit of the drug for the mother is higher than the risk of side effects in the fetus.

Made in Italy. Dispensed by prescription.

special instructions

It is recommended to prescribe Piracetam with caution to people with kidney disease, bleeding and homeostasis abnormalities. And also for people during and after operations.

Pregnancy and lactation

Animal studies confirmed the safety of the drug for the fetus. No comprehensive studies have been conducted on humans. Taking Piracetam during pregnancy is permitted provided that the expected benefit to the mother outweighs the potential risk to the child. A doctor's supervision is required. Taking medication during breastfeeding is allowed only when lactation is canceled.

It is forbidden to take Mexidol during pregnancy or breastfeeding. The effect of the drug on the child’s body and mother’s milk has not been studied.

Childhood

Mexidol is not used in pediatrics. Piracetam is prescribed to children.

Elderly age

Dosage adjustment is only necessary when treating elderly patients with liver and kidney diseases. During treatment, it is necessary to monitor kidney and liver parameters.

Cerebrolysin or Ceraxon

Ceraxon is a nootropic drug based on citicoline, prescribed for ischemic and hemorrhagic stroke, head injury and cognitive impairment. Often used for older people.

One of the differences between the analogue of the drug Cerebrolysin is the additional form in the form of an oral solution. It is packaged in a bottle with a dispenser syringe or disposable sachets.

Ceraxon ampoules are administered intramuscularly or intravenously, depending on the indications and severity of the patient’s condition. Then it is possible to enhance the effect with an oral solution.

The analogue restores damaged brain cells, improves cognitive functions, prevents the death of ischemic tissue, and reduces the severity of neurological manifestations of diseases.

Ceraxon differs from Cerebrolysin in its lower price and the presence of an additional release form - an oral solution. Both medications are used for recovery from TBI and stroke, and in cases of impaired cognitive function.

However, Cerebrolysin is also used in children with developmental delay, hyperactivity and attention deficit disorder, and Alzheimer's disease.

The mechanisms of action of drugs are different due to the incoming substances - Cerebrolysin consists of polypeptides, the cheap analogue Ceraxon contains citicoline.

Citicoline is also contained in the drugs Proneuro, Recognan, Neypilept, etc. Which is better is determined by the doctor specifically for each patient.

Cerebrolysin or Cerebrolysate

The two drugs have a similar mechanism of action and therapeutic effects and are available in ampoules. Cerebrolysate (Cellex substitute) is more effective for cerebral palsy, nerve root diseases, and after brain surgery. The route of administration is exclusively intramuscular.

Cerebrolysin is a studied Austrian drug for developmental delays in children and dementia, after a stroke. This means that as a result of clinical trials, indications, contraindications, side effects, and dosage regimens were determined. The medication is used intramuscularly, intravenously and as part of droppers. The only drawback is the high cost.

When choosing between analogues, one should take into account financial capabilities, efficiency and sufficient research.

Discuss the choice of analogues cheaper than Cerebrolysin with your doctor due to possible contraindications, side effects and nuances of prescription. Many drugs with similar effects are not sold freely in pharmacies. Before use, read the instructions for use.

Cerebrolysin reviews from doctors - what diseases can be cured with this medicine?

The main active component of Ceraxon is citicoline sodium. It inhibits the action of phospholipase, restores damaged brain cells, and prevents the formation of free radicals. The drug is administered intramuscularly, intravenously and taken orally.

The medicine is intended for both internal use and injection. Cerebrolysin also belongs to nootropic drugs. The main ingredient is peptides obtained from pig brain. The drug increases the energy metabolism of brain neurons and significantly improves protein production. The drug is available in the form of a solution for intramuscular injection.

Cerebrolysin and Ceraxon are used as part of complex rehabilitation therapy after ischemic and hemorrhagic stroke and traumatic brain injury. Both drugs are prescribed in the acute period of ischemic stroke. When choosing a medicine, doctors at the Yusupov Hospital take into account indications, contraindications, and possible side effects.

Recognan or Ceraxon - which is better? Ceraxon is a drug that has a neuroprotective effect. Its complete structural analogue is recognan. Both drugs contain the same active substance - citicoline sodium. The dosage forms of both drugs are the same: a solution for intravenous and intramuscular administration and a liquid for oral administration, which is available in sachets or a syringe dose.

The excipients that make up the solution for injection are also identical: sodium hydroxide, water for injection. The additional ingredients of the oral solution are various. Recognan contains additives - propylene glycol, synthetic sweetener, azorubine dye. They may cause an allergic reaction.

The main therapeutic effect of the drugs does not differ. Citicoline is a precursor to cell membrane components. When it enters the body, it has a positive effect:

Reduces the formation of free radicals;
Restores damaged nerve cell walls;
Prevents their death.

According to neurologists, the drugs are completely interchangeable. Ceraxon is produced in Spain, Recognan - in Russia. The price of five ampoules of Ceraxon is 1260 rubles, 30 ml of solution for oral administration is 760 rubles. Domestic drugs Recognan are cheaper. 5 ampoules of the drug can be purchased at a pharmacy for 570 rubles, an oral solution costs 440 rubles.

Patients often ask whether Ceraxon or Mexidol is better. Both drugs have a nootropic effect. Mexidol is prepared in the form of a solution for intravenous and intramuscular administration. The active component of the drug is ethylmethylhydroxypyridine succinate. The active ingredient in Ceraxon is citicoline sodium.

Indications for the use of Mexidol are broader than those of Ceraxon. Mexidol is prescribed not only for neurological pathology, but also as part of complex therapy for patients suffering from the following diseases:

Acute myocardial infarction (from the first day);
Primary open-angle glaucoma of various stages;
Withdrawal syndrome in alcoholism with a predominance of neurosis-like and vegetative-vascular disorders;
Acute intoxication with antipsychotic drugs;
Acute purulent-inflammatory diseases of the abdominal cavity.

Mexidol is produced in Russia, its price is less than the Spanish-made drug Ceraxon. What is better to take - Ceraxon or Actovegin? The main active ingredient of Actovegin is purified calf extract, and that of Ceraxon is citicoline sodium. Actovegin is a natural drug, and Ceraxon is a chemical substance. Both drugs have a nootropic effect, but act differently.

A doctor, when discussing the question of what to prescribe, Cerepro or Ceraxon, is based on the severity of the symptoms of the disease, the cost of the drugs and the financial capabilities of the patient. The Russian drug Cerepro is cheaper than the drug from the Spanish pharmaceutical company Ceraxon. The drugs are no different.

Dyscirculatory encephalopathy (DEP) is a gradually progressive organic change in brain tissue due to chronic cerebral vascular insufficiency, which is caused by various vascular diseases (arterial hypertension, cerebral atherosclerosis). With encephalopathy, pseudobulbar syndrome is observed:

Dysphonia;
Dysarthria (speech disorder);
Dysphagia (impaired swallowing).

These signs are combined with symptoms of oral automatism, increased pharyngeal and mandibular reflexes, forced laughter and crying. To treat DEP, neurologists at the Yusupov Hospital use effective drugs that have minimal side effects. Ceraxon and nootropil have a neuroprotective effect.

The active substance of nootropil is piracetam, and that of ceraxon is citicoline sodium. Nootropil is administered intravenously or taken orally in capsules. Ceraxon is available in the form of a solution for intramuscular, intravenous injection and for oral administration.

Deputy General Director for Medical Affairs, general practitioner, gastroenterologist, candidate of medical sciences

Today, there are quite a lot of different medications used in medical practice to treat impaired blood circulation in the brain. Therefore, patients are often faced with the difficulty of choosing one medicine or another.

It is a drug that helps regulate blood supply in the arteries inside the skull, which eliminates pathological development in brain cells by supplying them with oxygen. Thanks to this, memory and other parts of the organ become better, increasing a person’s intellectual capabilities, and neurons under its influence become more protected.

Also, under the influence of this drug, rapid recovery occurs after a heart attack and stroke. In addition, it effectively treats systemic disease of the cerebral arteries and coronary sclerosis, lowers cholesterol levels, and helps get rid of depression.

Available in the form of capsules, injections, and toothpaste for the treatment of dental diseases.

The following indications for use are distinguished:

Disturbance in cerebral blood supply.
Dysregulation of vascular tone.
Oxygen starvation caused by neurosis.
Hypoxia caused by a pathological condition during sudden cessation of alcoholic beverages in people with alcohol dependence.
Concussion and other head injuries.
Degeneration of neurons due to disruption of their blood supply.
Panic attacks.
Poisoning of the body with psychotropic drugs.
Postoperative interventions.
Nervous state after increased stress.

It has also shown itself to be effective in the treatment of cervical osteochondrosis, which impairs the blood supply to the brain.

Contraindicated in cases of liver failure, cessation of urine flow into the bladder, or hypersensitivity to the active ingredient. Does not affect coordination or blood pressure.

Adverse reactions may occur - nausea, dizziness, diarrhea, allergic reaction in the form of skin rashes.

There is no data on safe use in pregnant and lactating women, so it is recommended to avoid use in these cases.

It is a nootropic drug, which is a set of peptides obtained from pig brain.

Used in the treatment of patients with various neurological pathologies:

Alzheimer's disease.
Traumatic lesions of the brain and spinal cord.
Complications after a stroke.
Acute cerebral circulatory failure.
Cerebrovascular syndrome.
Mental retardation in children.
Increased motor activity in children and lack of attention.
Acquired dementia syndrome.

Available in the form of a solution for intravenous and intramuscular administration. There is no tablet form of release.

Side effects occur in rare cases when the medicine is administered too quickly. You may experience a feeling of heat, increased sweating, dizziness, and rapid heartbeat. The dosage and duration of therapy depends on the patient’s age, characteristics of the body, type and stage of the disease.

It has some contraindications that must be taken into account:

High sensitivity to active substances.
Acute kidney diseases.
Allergic diathesis.
Epilepsy.

During pregnancy, the drug is allowed only in case of urgent need under strict medical supervision. If use is necessary during the lactation period, then the breastfeeding process must be suspended for a while due to the lack of study data.

The medications in question belong to the same pharmacological group of nootropics. They have one area of application - neurology. Both drugs improve metabolic processes in the brain, as well as metabolism in neural tissues at the cellular level. After the administration of these drugs, the following reactions occur:

Increasing the efficiency of catabolism and cellular respiration.
Increased protein synthesis.
Increased concentration of the hormone responsible for the psycho-emotional state of a person.
Increasing the body's resistance to temporary oxygen starvation.
Prevention of neuronal death.
Improvement of cerebral microcirculation.

They also ensure the rapid release of toxic substances from the body during alcohol and drug poisoning.

Despite the fact that the drugs are part of the same nootropic group, they have different subgroups, which means different areas of application and mechanism of action on the body. Experts do not consider them absolute analogues.

Mexidol is an antioxidant that stops oxidation processes in the body and improves cerebral circulation. And another remedy refers to polypeptides responsible for the quality of functioning of the cerebral cortex. Therefore, it is not advisable to inject them together.

Side effects

After administering Mexidol and Actovegin to a patient, in some cases side effects may occur. These include:

the occurrence of allergic reactions;
drop in blood pressure;
dizziness.

You must immediately report any unpleasant symptoms that occur to your doctor.

To treat circulatory disorders in the brain in adults and children from the day of birth, as well as to support the emotional state of pregnant and breastfeeding mothers, the nootropic drug Cortexin is prescribed.

Cortexin has a complex of low molecular weight polypeptide fractions that penetrate through the BBB to nerve cells. It has nootropic, neuroprotective, antioxidant and tissue-specific effects.

And:

improves brain function, learning and memory processes, concentration, resistance to stress;
protects neurons from damage, reduces the toxicity of psychotropic drugs;
has anticonvulsant and cerebroprotective properties;
Helps quickly restore central nervous system functions after stress.

The advantage of Cortexin is its rapid effect on the brain, since the active substance of this drug acts directly on brain cells. The drug does not have many side effects compared to other similar medications. Recommended for children from birth, pregnant and nursing mothers. A very inexpensive product.

The disadvantages include:

the injections are painful, but if you replace the water with novocaine, the injections will not be so scary, especially for children;
the product is not produced in the form of tablets and capsules, so if it is impossible to give an injection, you need to look for analogues of Cortexin in tablets.

Two companies, two prices

The powder is diluted with water for injection or novocaine, since the injection is very painful and for children this is a big disadvantage.

The drug is produced only in Russia by two pharmacological companies: Geropharm LLC - it was the first to produce the drug and its drug is more expensive than the second one.

According to patient reviews, the drug from the first manufacturer is considered reliable. They have the same composition and release form too. They differ in price, but not significantly.

The drug has no analogues in terms of structural composition, but there are a number of medications similar to it in terms of the mechanism of action. TOP 15 analogues of Cortexin, which are available both in tablets and ampoules:

Aminalon - available in tablet form, its active substance is gamma-aminobutyric acid.
Actovegin is produced in the form of solutions for intravenous and intramuscular use and tablets. The active substance is an extract from the blood of calves, freed from protein.
Glycine – produced in the form of sublingual tablets. The active ingredient is microencapsulated glycine.
Lucetam – tablets and solution for intravenous and intramuscular injections. The active substance is piracetam.
Nootropil is produced in the form of tablets and capsules, as well as in the form of a solution for oral administration and for intravenous and intramuscular administration. The active substance is piracetam.
Pantogam - available in the form of tablets and syrup. The active substance is the calcium salt of hopantenic acid.
Piracetam - produced in the form of tablets and capsules, as well as a solution for injections. The active ingredient is piracetam.
Mexidol is produced only in the form of tablets with the active substance – ethylmethylhydroxypyridine succinate.
Tonoten is a lozenge and is a homeopathic remedy. It contains antibodies to the brain-specific protein S-100 in a large dilution.
Tenoten for children is a tablet containing an active substance - a protein, an antibody that specifically interacts with the S-100 protein, which is found in human nervous tissue.
Phenotropil are tablets with the active substance – phenotropil.
Ceraxon - produced in the form of a solution for internal use and injections, both intramuscular and intravenous. Active substance: citicoline sodium.
Cerebrolysin is a solution for injection in various packaging. The active substance is a complex of peptides from the pig brain.
Encephabol is produced in the form of tablets and suspensions for oral administration. The active ingredient is pyritinol dihydrochloride monohydrate.
Nikomex is a solution for injections. The active ingredient is ethylmethylhydroxypyridine succinate.

There are other drugs that produce a similar effect on the patient’s brain as Cortexin, but these analogues are cheaper (almost all) and no less effective.

To start treatment, you must consult a doctor; self-medication is not recommended.

We compared Cortexin and its most popular competitor analogues and this is what we got.

Both drugs restore cerebral circulatory function and are used after traumatic brain injuries and for mental retardation in children.

Cerebrolysin is used for strokes, spinal cord injuries, for the treatment of endogenous depression, autism, and enuresis.

Cortexin is used for deterioration of memory and thinking, encephalopathy, epilepsy, encephalitis, cerebral palsy in newborns, delayed speech and motor development and poor learning ability of children. Both drugs are used to treat autism spectrum disorders in children from the first year of life.

The simultaneous use of Cortexin and Cerebrolysin in cardiology restores the main indicators of heart function. In ischemic stroke, both drugs act equally, reducing the number of deaths.

In case of delayed speech development, both drugs act equally, but Cortexin has a side effect - agitation of the child. Both drugs cannot be used during pregnancy and lactation, as they can cause allergies. Cerebrolysin, in turn, cannot be used in case of epilepsy and renal failure.

The price of Cortexin is 2 times cheaper than Cerebrolysin, therefore, given their identical properties, preference is given to the former.

Both drugs belong to nootropics, the active substance of which is of animal origin. They have similar indications for use, but a nootropic drug is also prescribed with Actovegin.

Cortexin treats dyscirculatory encephalopathy well, and Actovegin helps with this pathology only in combination with other medications.

Cortexin remains the only drug in the treatment of newborns with CNS injuries that gives a positive result. Chronic fatigue syndrome is eliminated faster when using Cortexin.

Both drugs cause allergies, but combine well with other medications.

Cortexin is contraindicated during pregnancy and lactation, and Actovegin costs a little less.

Both drugs have similar indications for use:

encephalopathy;
memory and thinking disorders;
decreased learning ability;
absent-mindedness.

Both have powerful neuroprotective effects and regulate dopamine levels in the brain. They are good to use in combination in the treatment of traumatic brain injuries (they give high-quality and quick results), as well as for ischemic brain lesions.

This treatment is prescribed by a doctor and is carried out strictly under his supervision. Mexidol and Cortexin cannot be used during pregnancy, breastfeeding, acute renal failure, and the first drug cannot be used in acute liver failure.

They are approximately the same price.

Both are nootropics, but with different active ingredients. Cerakson is more effective than Cortexin for relieving cerebral edema, therefore, after its use, memory or attention is restored more quickly.

It can be used both in the acute period of the disease and during the rehabilitation period.
Cerakson has more contraindications - they cannot treat children from birth.
And also the short duration of the course of treatment.
The price of Ceraxon is also high compared to Cortexin.

Cortexin interacts slightly with other drugs. Therefore, it is used in the complex treatment of many diseases. There was no information about adverse effects.

All complex prescriptions are made by a doctor and monitors the treatment process. The drug is prescribed on the recommendation of the attending physician; he also decides whether to use its analogues

The drugs have a high coefficient of action and are very often used. Despite frequent joint use, each drug has its own specifics:

In cases of direct treatment of cerebral circulation, hypoxia, and fetal hypoxia, preference is given to Actovegin.
Mexidol is used in more severe cases with a wide range of symptoms. However, doctors recommend using these drugs together.

Among the negative consequences in terms of frequency of manifestation, allergic reactions to drug components, including anaphylactic shock, predominate. People with hypersensitivity should use these drugs only after consulting a doctor.

Side effects of taking Actovegin are:

violation of the breakdown of food in the stomach;
dry mucous membranes;
pain in the heart, high or low blood pressure;
feeling of tightness in the chest;
labored breathing;
pain in muscles and joints.

Typical side effects when using Mexidol are:

insomnia;
increased feelings of anxiety and phobias;
emotional overexcitation;
cerebellar dysfunction;
disorientation in space;
high or low blood pressure;
malaise, feeling of weakness.