Mydocalm injections. patient reviews, instructions for use, analogues, price


Mydocalm and Sirdalud: contraindications for use

2. Functional diseases of the spinal column.

Table of contents:

The dosage in such cases is selected depending on the reaction to the drug and the severity of symptoms.

  • The initial dosage is 2 mg three times a day.
  • After a few days, you can increase the dosage of namg.
  • The optimal daily dosage is from 12 to 24 mg.
  • Dosages above 36 mg per day are fraught with the development of side effects.

2. Dosage for elderly patients.

The dosage for elderly people is adjusted. Such patients should be under constant supervision of medical personnel. Most often, the dosage is reduced because renal clearance (the rate at which the kidneys excrete various substances from the blood) is slower in older people.

For renal failure, the average dosage is 2 mg three times a day. Depending on the further clinical picture and the tolerability of the drug, the dosage and frequency of administration are adjusted.

  • Severe renal and hepatic dysfunction.
  • Overreaction to tizanidine.
  • Combination of tizanidine with fluvoxamine.
  • Tizanidine.
  • Tizanidine hydrochloride.
  • Tizanil.
  • Tizalud.

I took Sirdalud two years ago when I was treated by a neurologist. Then, I remember, he helped me a lot. I drank it for almost two months.

Mydocalm or sirdalud which is better reviews

My neck hurts every day, it’s all from osteochondrosis and from office work. It hurts so much that it’s difficult to find a normal body position for sleeping, and I end up tossing and turning in bed half the night. When the doctor recommended that I take a course of treatment with Sirdalud, I was completely exhausted by pain in my neck and shoulders. But now, a month later, I feel some relief.

My grandfather (he is 75 years old) began to have problems with blood circulation, and this is in addition to his long-standing radiculitis. He was prescribed drugs to improve blood circulation and muscle relaxants. After the Sirdalud course, he definitely felt better.

I recently had a hernia removed, and after the operation, I was prescribed Sirdalud. The doctor said that thanks to this remedy the pain will decrease and the muscles will be able to relax. This is what happened, so the drug is effective.

A comparison of the drug Sirdalud with Mydocalm shows that they have slight differences in indications for use.

Sirdalud is advisable to use in the treatment of:

  • Convulsive lesions of the limbs;
  • Severe muscle spasms.

Mydocalm should be taken by patients who suffer from:

  • Pathological hypertonicity;
  • Muscle rigidity;
  • Pain during active movement.

Mydocalm is contraindicated in the following cases:

  • The patient has hypersensitivity to the constituent components;
  • Myasthenia;
  • Infants under 12 weeks.

Sirdalud is not prescribed for:

  • Liver diseases;
  • Intolerance to the composition of the drug;
  • The patient is taking Fluvoxamine;
  • The patient has not reached 18 years of age.

Patients are prohibited from taking Mydocalm and Sirdalud at the same time, since this combination minimizes the therapeutic effect of each of them and provokes the development of side effects. One of these drugs may be part of complex therapy, but taking any of them as self-medication is strictly prohibited.

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You can get an idea of ​​how the drug Sirdalud acts on the body and what negative reactions it causes from patient reviews.

“The muscle relaxant Sirdalud saves me. For many years now I have been suffering from osteochondrosis of the lumbar and thoracic spine. I treat this pathology periodically when the pain is unbearable. This medication is a good pain reliever and relieves muscle spasms. I take tablets in the minimum dosage – 2 mg, and only before bed.

I can’t afford a larger dosage, since Sirdalud causes severe drowsiness and inhibits many reactions. I drive, so side effects from taking pills and transportation are incompatible concepts.

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We have selected real reviews about the drug Sirdalud, which are published by our users. Most often, reviews are written by mothers of young patients, but they also describe their personal history of using the drug on themselves.

- painful muscle spasm associated with static and functional diseases of the spine (cervical and lumbar syndromes), as well as after surgical interventions (for example, for a herniated disc or osteoarthritis of the hip joint);

- spasticity of skeletal muscles in neurological diseases, for example, multiple sclerosis, chronic myelopathy, degenerative diseases of the spinal cord, consequences of cerebrovascular accidents and cerebral palsy (patients over 18 years of age).

If you are deciding which is better to buy: Mydocalm or Sirdalud, you need to study the composition and properties of both products. In this case, the active substance, its concentration, the principle of its effect on the body, and the method of application are compared.

Pay attention to contraindications and side effects. However, it is possible to determine which medicine is more effective only by correlating its properties and principle of action with the characteristics of the disease. Even an expensive drug does not help in 100% of cases.

Available in the form of tablets and solution for injection. The main component is the substance tolperisone hydrochloride. Contained in different concentrations, 50 and 150 mg in tablets and 100 mg in ampoules. When prescribing an injection solution, you need to take into account that the composition, among other things, also includes lidocaine. This substance is contraindicated in a number of pathological conditions.

The drug Mydocalm is a muscle relaxant drug. It affects the central nervous system. The active substance tolperisone interferes with the conduction of impulses in neurons. This leads to blocking of spinal reflexes.

The active substance stabilizes cell membranes, prevents the penetration of sodium and calcium into the membranes of nerve cells. During administration, there is no sedative effect. Soon after the start of therapy, pain in the affected area disappears.

Vasily Patronov, 56 years old, Karaganda

Mydocalm gave me only short-term relief. Sirdalud lasts longer, but while using it, you constantly feel sleepy. Therefore, to avoid problems, it is necessary to avoid driving during treatment.

Irina Samovolova, 34 years old, Krasnodar

I used both drugs at different times. Mydocalm suited me better, because... it contains lidocaine. The pain goes away instantly. Sirdalud acts more slowly, but lasts longer.

Characteristics of Sirdalud

The active component of this muscle relaxant is tizanidine. The medicine inhibits the process of nervous excitation and the release of amino acids, and also affects neuromuscular transmission and the condition of the spine.

The remedy is indicated in the following situations:

  • muscle spasms due to spondylosis, osteochondrosis of the cervical spine;
  • recovery after surgical interventions on the back and other parts of the musculoskeletal system;
  • muscle spasms caused by dysfunction of the central nervous system and brain.

It is forbidden to use Sirdalud if liver function is reduced, if you are a minor, or if you are allergic to substances from its composition. During lactation and pregnancy, using the medication is also undesirable, because

Clinical studies of the drug's effects on fetal development have not been conducted. During pregnancy, the drug can be prescribed only for exceptional indications and under close medical supervision.

General information about the drug

Mydocalm is recommended for use in the following cases:

  • muscle hypertonicity, spasms of striated muscles in diseases of the central nervous system (encephalomyelitis, stroke as a result of blockage of cerebral vessels, multiple sclerosis, myelopathy);
  • muscle hypertonicity and spasms in diseases of the musculoskeletal system (arthrosis, spondylosis, lumbar syndrome, spondyloarthrosis);
  • rehabilitation therapy after surgery (as a result of orthopedic disorders, injuries);
  • diseases of the vascular system, namely obliterating atherosclerosis and thromboangiitis, diffuse scleroderma, Raynaud's disease;
  • types of encephalopathy characterized by muscular dystonia.

The drug has few contraindications, but they are all quite serious. Mydocalm is not used for epilepsy and myasthenia. The drug is prohibited for use by children under 3 years of age. During pregnancy and lactation, Mydocalm is used only when the likely benefit outweighs the harm.

This is because the effect of the active compound on the fetus has not been studied. Do not use the drug if an allergic reaction occurs as a result of individual intolerance to some components of the drug.

The dosage of the drug in tablets is determined by the age of the patient and can vary from 5 to 150 mg per day. The amount of solution for injection also changes, but depending on the method of administration. It can be administered intramuscularly at 100 mg per day (total 200 mg), and intravenously at 100 mg per day. Side effects are as follows:

  • hypotension;
  • general weakness;
  • headache;
  • disorders of the digestive tract (nausea, vomiting);
  • Less common are allergic reactions, which are manifested by redness of the skin, rash, itching, urticaria, anaphylactic shock, bronchospasm.

If side effects occur, it is recommended to reduce the dosage of the drug. If relief does not occur, the medicine is discontinued and its analogue is administered. Considering that Mydocalm does not depress the nervous system, it can be used along with sedatives.

However, some drugs enhance the effect of the active substance in Mydocalm on the body. These include psychotropic medications and drugs used for general anesthesia. This must be taken into account when calculating the dosage of Mydocalm. This drug can be taken at the same time as other medications.

The drug is released in the form of tablets. This remedy works as follows:

  • relieves spasm;
  • reduces muscle tone;
  • has a moderate analgesic effect;
  • increases the range of active movements;
  • relaxes the muscles of the musculoskeletal system;
  • reduces the frequency of chronic seizures.

Note! The medication is suitable for use in both acute and chronic diseases.

Indications for taking Sirdalud are:

  • painful muscle spasm due to diseases of the spinal column;
  • period after surgery;
  • various neurological diseases (multiple sclerosis, cerebral palsy).

Important! The drug Sirdalud can be used to relieve pain in osteochondrosis of any part of the spine of the second and third degrees of development.

Contraindications to the use of this muscle relaxant are:

  • age under 18 years;
  • periods of gestation and breastfeeding;
  • increased sensitivity of the body to the components included in the drug;
  • severe renal dysfunction;
  • severe liver diseases.

Relative contraindications to the use of Sirdalud are old age (over 65 years), moderate abnormalities in the liver and kidneys. For elderly patients, Sirdalud for cervical osteochondrosis is prescribed in exceptional cases and in moderate doses.

Side effects

Mydocalm is usually easily tolerated, and side effects were rarely observed in studies. The summary of the medication contains a list of possible adverse events. In order of frequency of occurrence, in decreasing order, these are:

  • sleep problems, headache, dizziness, anorexia;
  • decreased muscle strength, pain in the limbs, general weakness, fatigue;
  • gagging, up to the eruption of stomach contents, a feeling of heaviness in the stomach, dry mouth;
  • drop in blood pressure, difficulty breathing, rapid heartbeat, ringing in the ears, nosebleeds, hot flashes;
  • allergic reaction - skin rashes, itching, redness of the skin, increased sweating, Quincke's edema, bronchospastic syndrome, anaphylaxis.

The instructions prohibit drinking alcohol during the treatment period and for another 2 weeks after completion of the course, because the combination is fraught with the development of bradycardia, tachycardia, postural hypotension, and acute heart failure. No other restrictions are imposed, but it must be taken into account that when taken together with NSAIDs, general anesthetics, other muscle relaxants, Clonidine or psychoactive substances, dose adjustments may be required.

Features of Mydocalm

This product is available in the form of tablets and infusion solution. Its active ingredient is tolperisone hydrochloride. The list of components of the drug in soluble format includes lidocaine.

The principle of action of Mydocalm is that its active ingredient inhibits the conduction of nerve impulses, suppressing spinal reflexes. The drug reduces muscle tone. Tolperisone hydrochloride prevents the penetration of sodium and calcium into nerve cells.

The medicine is indicated for:

  • increased muscle tone;
  • muscle spasms occurring against the background of myelopathy, stroke, arthrosis or multiple sclerosis;
  • recovery after operations on the musculoskeletal system;
  • pain syndrome caused by injuries;
  • diffuse scleroderma;
  • Raynaud's syndrome;
  • thromboangiitis;
  • cerebral encephalopathy, which is accompanied by muscular dystonia.

The drug has restrictions on its use. Among them:

  • epilepsy;
  • myasthenia gravis;
  • age less than 3 years;
  • allergy to substances contained in the medication.

When taking Mydocalm, the following negative reactions may occur:

  • pronounced decrease in blood pressure;
  • feeling of drowsiness and weakness;
  • headache;
  • Digestive problems.

If there are side effects, you should stop taking the medication and consult a doctor.

When taking Mydocalm, negative reactions such as a pronounced decrease in blood pressure may occur.

These drugs are included in one pharmacological category - muscle relaxants. However, they have different compositions.

The medications have similar indications for use - they are used in the treatment of pathologies of the musculoskeletal system, as well as to speed up recovery after injuries and operations.

Medicines have not only different compositions, but also different dosages. This must be taken into account when replacing them with each other.

The daily dose of Sirdalud is determined individually. The maximum amount of muscle relaxant per day should be no more than 36 mg.

The instructions for the drug Mydocalm say that it should be taken 450 mg per day (in 3 divided doses). To check the body's tolerance of the drug, therapy should begin with a dose of 50 mg. In the absence of side effects, the dosage regimen should be gradually increased.

Pharmaceutical products also have some differences in contraindications. The drug Sirdalud has more of them. In addition, it has more side effects.

The drug Sirdalud does not contain lidocaine. Mydocalm can be used to treat children over 3 years of age, and its analogue can only be used in adult patients.

When choosing a suitable medicine, a number of factors are taken into account - the composition, release form, dosage of the active component, type of excipients, contraindications and side effects. Pay attention to reviews, but different drugs have different effects on the body of patients with certain pathologies. If the medicine helps some, others experience side effects.

Mydocalm and Sirdalud represent the same group (muscle relaxants), but these are drugs with significant differences. The first of these has fewer restrictions on use and is characterized by a small number of side effects, but the injection solution contains lidocaine.

Sirdalud provokes the occurrence of various side effects; it is not used for a large number of pathological conditions. This drug is restricted for use in children and the elderly (under 18, over 65 years). It does not contain lidocaine, which is a plus in some situations.

The cost of both drugs is low, but Mydocalm will cost a little more than Sirdalud. Thus, the first of these medications is offered at an average price of 400–600 rubles, the second can be purchased in the range from 200 to 500 rubles.

Kinetics

Tab. “Mydocalm” allows you to deliver tolperisone, an active ingredient, which has a good ability to be absorbed during the passage of the gastrointestinal tract, into the patient’s body. On average, the maximum concentration of the component in the circulatory system is recorded 30-60 minutes after taking the medication. Bioavailability is estimated at 20 percent. Transformation processes are localized in the liver and kidneys. The products of such a reaction have not yet been sufficiently studied, so experts do not have the opportunity to determine whether they are active in relation to the human body. Tolperisone is predominantly eliminated by urine in the form of transformation products. This excretion accounts for more than 99% of the substance entering the body.

Which is better, comparison

Sirdalud or Mydocalm, which is what doctors and their patients who have taken both drugs know better. When choosing a suitable product, the form of release, composition, dose, interaction with other drugs, negative consequences and overdose are taken into account.

In order not to make a mistake in choosing medications, you should study their principle of action. Thus, Sirdalud contains tizanidine, which acts on adrenergic receptors located in the spinal cord. This leads to blockage of spinal nerve cells, which weakens muscle tone. In addition, tizanidine has a moderate analgesic effect.

The action of Sirdalud occurs quite quickly. The highest amount of the base substance in the blood is observed 1 hour after application.

Mydocalm also belongs to the muscle relaxants, but the effect of tolperisone is slightly different. The main component of the drug normalizes the function of the caudal region, which inhibits the hyperexcitability of the spinal cord. The medicine affects nerve endings in the periphery.

Mydocalm has a quick effect. The highest content of the basic component in plasma occurs 30 minutes after administration.

If you compare drugs according to indications, you cannot understand which is better than Tizanidine and Mydocalm, since both drugs are used in identical cases.

But still the drugs have some differences in indications. So Sirdalud is used in the treatment of diseases of spinal and cerebral origin. Tizanidine quickly eliminates spasms and convulsions and increases the contractility of skeletal muscles.

Mydocalm has a large list of indications. It eliminates muscle rigidity and hypertonicity. The medicine also promotes the conduction of fluid into the tissue.

Comparison of Mydocalm and Sirdalud according to contraindications - the use of drugs is prohibited in case of hypersensitivity to the composition of the drugs, in childhood and old age, in case of lactose intolerance and pregnancy. Mydocalm is also not used for myasthenia gravis.

Differences between drugs according to method of application:

  1. The average dose of Sirdalud is 2-4 mg, which is divided into three doses per day.
  2. The recommended amount of Mydocalm is 150-450 m, divided into 3 doses.

Therapists know whether Sirdalud and Mydocalm can be taken at the same time. Doctors draw the attention of their patients to the fact that both drugs are muscle relaxants that affect the central nervous system. Therefore, theoretically, medications can be combined, but only as prescribed by a doctor.

It is noteworthy that Sirdalud has more adverse reactions, such as xerostomia, drowsiness, dizziness, hypotension, malaise, bradycardia, etc. And Mydocalm often causes myalgia, digestive disorders and headaches.

If you compare drugs by price, it is worth noting that Mydocalm is more expensive. Its approximate cost is 350 rubles. The price of Sirdalud is 40% less.

So, it is impossible to say unequivocally that Sirdalud or Mydocalm is better. These are two good remedies that are effective for osteochondrosis and other pathologies of the musculoskeletal system.

Sirdalud is considered a more modern remedy. In addition, the drug is available in a special dosage form, due to which there is a slow and prolonged release of tizanidine. This allows you to take the tablets once and minimize the risk of negative reactions.

Mydocalm is a well-studied drug with a more extensive list of indications. But you need to take the tablets three times a day.

The drugs have similar effects and the same level of effectiveness. However, Sirdalud lasts longer, because its active component spends more time in the blood plasma.

Mydocalm contains lidocaine, so it helps to get rid of painful sensations faster.

Both drugs are muscle relaxants that exhibit central action. This means that substances in this category affect the transmission of nerve impulses directly to the central nervous system, and not to the periphery (in the muscles).

Which is correct?

The dosage of Mydocalm tablets will be determined by the attending doctor. The drug is intended for oral administration. Do not chew capsules. Each copy must be washed down with clean water without additives in a reasonable volume. For persons over fourteen years of age and adult patients, Mydocalm is initially prescribed in the amount of 50 mg up to three times daily. The dose is gradually increased. Maximum – 150 mg three times every day. If it is necessary to formulate a therapeutic course for children over three years of age, but under six years of age, the dosage should be calculated based on weight. For every kilogram you need to take 5 mg of the drug. The daily volume is divided into three servings. For children older than this age group, but under 14 years of age, it is recommended to calculate the dose as 3 mg/kg with a possible deviation of 1 mg up or down. The daily volume is divided into three servings.

Doctors' opinion

Karina Bolshakova (traumatologist), 43 years old, Murom

These pharmaceutical products have the same pharmacokinetic and therapeutic profiles and are therefore interchangeable. They are available in tablet form. But in cases where you need to quickly eliminate severe pain, it is better to choose Mydocalm, because it additionally contains the anesthetic lidocaine.

Anatoly Sapozhkov (traumatologist), 32 years old, Arkhangelsk

The drug Sirdalud does not contain lidocaine, which is both its advantage and disadvantage. The advantage is that this substance helps to quickly relieve pain, but the disadvantage is that some patients are allergic to it. At the same time, Sirdalud is more often used for long-term therapy, and Mydocalm for emergency cases.

Instructions for use, dosage

The medication is intended for parenteral use. In this case, injections are performed intramuscularly.

As therapy, 100 mg of the drug is prescribed 2 times a day.

When using the drug in patients suffering from mild to moderate degrees of renal dysfunction, constant monitoring is required to monitor the patient's condition. If necessary, the dosage can be adjusted downwards. In severe forms of functional kidney disorders, the drug is not used.

Patients with moderate hepatic disorders require constant monitoring and dosage adjustment downward. For severe liver dysfunction, the medicine is not prescribed.

What is better for osteochondrosis: Sirdalud or Mydocalm?

Neck pain is familiar to many people. The main reason is osteochondrosis. The disease is the result of a sedentary lifestyle: prolonged work at the computer, driving a car. Poor nutrition and bad habits also have a detrimental effect on the condition of this part of the spine.

It is necessary to treat cervical osteochondrosis in the early stages to prevent the development of complications. Only a doctor can prescribe appropriate therapy. For treatment to be effective, you should undergo an examination recommended by a neurologist. To achieve a positive result, it is better to use an integrated approach.

To understand why this or that treatment is prescribed for osteochondrosis of the cervical spine, you need to remember a little what kind of disease it is. It is based on changes in discs, vertebrae, ligaments and joints. Bone outgrowths and hernias can affect muscles, vertebral arteries, the spinal cord and its roots.

The resulting pain syndrome causes a reflex muscle spasm. Narrowing of the arteries is accompanied by impaired cerebral circulation. When the spinal root is compressed, pain and numbness in the arm are observed.

Prescription of medications is mandatory in the treatment of neck osteochondrosis. There are a lot of such funds. They help cope with the main symptoms of the disease.

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